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Determination of serum zinc-alpha-2-glycoprotein in patients with metabolic syndrome by a new ELISA.
OBJECTIVES To develop an assay for the determination of ZAG in human serum, and to investigate its clinical relevance as a marker of metabolic syndrome. DESIGN AND METHODS A new sandwich ELISA wasExpand
Cytotoxic activities of several geranyl-substituted flavanones.
Nine geranylated flavanones isolated from the fruits of Paulownia tomentosa (4-12) and two from the roots of Morus alba (13 and 14) were examined for cytotoxicity to selected human cancer cell linesExpand
Marine natural products: Bryostatins in preclinical and clinical studies
Abstract Context: Bryostatins represent an important group of pharmaceutically promising substances. These compounds are produced by commensal microorganisms naturally occurring in marineExpand
Natural compound cudraflavone B shows promising anti-inflammatory properties in vitro.
Cudraflavone B (1) is a prenylated flavonoid found in large amounts in the roots of Morus alba, a plant used as a herbal remedy for its reputed anti-inflammatory properties. The present study showsExpand
Cytotoxicity and effects on inflammatory response of modified types of cellulose in macrophage-like THP-1 cells.
The cytotoxicity and in vitro effects of six variously modified types of cellulose (OC--oxidized cellulose, NaOC--oxidized cellulose sodium salt, DAC--dialdehyde cellulose, CMC--carboxymethylExpand
Geranylated flavanone tomentodiplacone B inhibits proliferation of human monocytic leukaemia (THP‐1) cells
Paulownia tomentosa is a rich source of geranylated flavanones, some of which we have previously shown to have cytotoxic activity. To identify members of this class of compounds with cytostaticExpand
Prenylated Flavonoids from Morus alba L. Cause Inhibition of G1/S Transition in THP-1 Human Leukemia Cells and Prevent the Lipopolysaccharide-Induced Inflammatory Response
Morus alba L. (MA) is a natural source of many compounds with different biological effects. It has been described to possess anti-inflammatory, antioxidant, and hepatoprotective activities. The aimExpand
Carvedilol Protects against Cyclosporine Nephropathy in Rats
Kotolova H., P. Kollar, M. Jaro‰ova: Carvedilol Protects against Cyclosporine Nephropathy in Rats. Acta Vet. Brno 2006, 75: 85-89. The aim of our experimental work was to study whether carvedilol isExpand
Flavonoid 4′-O-Methylkuwanon E from Morus alba Induces the Differentiation of THP-1 Human Leukemia Cells
Aims. In this work we studied cytodifferentiation effects of newly characterized prenyl flavonoid 4′-O-methylkuwanon E (4ME) isolated from white mulberry (Morus alba L.). Main Methods. Cell growthExpand
Treatment with atorvastatin reduces serum adipocyte‐fatty acid binding protein value in patients with hyperlipidaemia
Background  Adipocyte‐fatty acid binding protein (A‐FABP) is a circulating protein expressed in adipocytes and macrophages. Several recent studies demonstrated that A‐FABP might be involved in theExpand