P. Kohl | Semantic Scholar

Structural and functional characterisation of cardiac fibroblasts.

P. Camelliti, T. Borg, P. Kohl
Biology, Medicine
Cardiovascular research
2005

P. Kohl, E. Crampin, T A Quinn, D. Noble
Biology
Clinical pharmacology and therapeutics
1 July 2010

This article illustrates that this approach is productive for the exploration of systems behavior, or “phenotypes,” at all levels of structural and functional complexity, explicitly including the supracellular domain, and suggests how this may be related conceptually to genomes and biochemical networks.

View on Wiley

Electrical coupling of fibroblasts and myocytes: relevance for cardiac propagation.

P. Kohl, P. Camelliti, F. Burton, Godfrey L. Smith
Biology
Journal of electrocardiology
1 October 2005

View on PubMed

Macrophages Facilitate Electrical Conduction in the Heart

M. Hulsmans, S. Clauss, M. Nahrendorf
Biology, Medicine
Cell
20 April 2017

View on Elsevier

Improved guinea-pig ventricular cell model incorporating a diadic space, IKr and IKs, and length- and tension-dependent processes.

D. Noble, A. Varghese, P. Kohl, P. Noble
Biology
The Canadian journal of cardiology
1998

The guinea-pig ventricular cell model, originally developed by Noble et al in 1991, has been greatly extended to include accumulation and depletion of calcium in a diadic space between the sarcolemma and the sarcoplasmic reticulum and has been found to reliably reproduce experimental observations.

View on PubMed

Force-length relations in isolated intact cardiomyocytes subjected to dynamic changes in mechanical load.

G. Iribe, M. Helmes, P. Kohl
Biology, Engineering
American journal of physiology. Heart and…
1 March 2007

The ability of the present system to independently and dynamically control preload, afterload, and transition between end-diastolic and end-systolic FL coordinates provides a valuable extension to the range of tools available for the study of single cardiomyocyte mechanics, to foster its interrelation with whole heart pathophysiology.

View on PubMed

Effects of fibroblast-myocyte coupling on cardiac conduction and vulnerability to reentry: A computational study.

Yuanfang Xie, A. Garfinkel, P. Camelliti, P. Kohl, J. Weiss, Z. Qu
Biology, Medicine
Heart rhythm
1 November 2009

View on PubMed

Development of an anatomically detailed MRI-derived rabbit ventricular model and assessment of its impact on simulations of electrophysiological function

M. Bishop, G. Plank, P. Kohl
Biology
American journal of physiology. Heart and…
20 November 2009

Developing a highly detailed finite-element computational model of rabbit ventricles constructed from high-resolution MR data, including the processes of segmentation, identification of relevant anatomical features, mesh generation, and myocyte orientation representation, highlights the utility of histoanatomically detailed models for investigations of cardiac function, in particular for future patient-specific modeling.

View on PubMed

Fibroblast Network in Rabbit Sinoatrial Node: Structural and Functional Identification of Homogeneous and Heterogeneous Cell Coupling

P. Camelliti, C. Green, I. LeGrice, P. Kohl
Biology
Circulation research
2 April 2004

The findings show that cardiac fibroblasts form a coupled network of cells, which may be functionally linked to myocytes in rabbit SAN, which was investigated by dye transfer in sinoatrial node tissue explants.

View on Wolters Kluwer

Mechanosensitive fibroblasts in the sino‐atrial node region of rat heart: interaction with cardiomyocytes and possible role

P. Kohl, A. Kamkin, I. Kiseleva, D. Noble
Biology, Medicine
Experimental physiology
1 November 1994

Results show that cardiac mechanosensitive fibroblasts could form a cellular basis for the positive chronotropic response of the heart to stretch of the right atrium.

View on Wiley