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Genetic studies of body mass index yield new insights for obesity biology
TLDR
A genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in up to 339,224 individuals provide strong support for a role of the central nervous system in obesity susceptibility. Expand
Flavonoid intake and risk of chronic diseases.
TLDR
The risk of some chronic diseases may be lower at higher dietary flavonoid intakes, and a trend toward a reduction in risk of type 2 diabetes was associated with higher quercetin intakes. Expand
Major types of dietary fat and risk of coronary heart disease: a pooled analysis of 11 cohort studies.
TLDR
The associations suggest that replacing SFAs with PUFAs rather than MUFAs or carbohydrates prevents CHD over a wide range of intakes. Expand
Prevalence, determinants, and consequences of chronic neck pain in Finland.
TLDR
The distribution, determinants, and consequences of chronic neck pain have hitherto been described inadequately, and there was some independent association between neck syndrome and disabilities, use of physician services, and use of pain killers. Expand
Flavonoid intake and coronary mortality in Finland: a cohort study
TLDR
Flavonoids offer an explanation for the suggested beneficial effect of fruits and vegetables in coronary heart disease and people with very low intakes of flavonoids have higher risks of coronary disease. Expand
Association of overweight with increased risk of coronary heart disease partly independent of blood pressure and cholesterol levels: a meta-analysis of 21 cohort studies including more than 300 000
TLDR
Even for moderate overweight, there is a significant increased risk of CHD independent of these traditional risk factors, although confounding (eg, by dietary factors) cannot be completely ruled out. Expand
Antioxidant vitamin intake and coronary mortality in a longitudinal population study.
TLDR
The hypothesis that antioxidant vitamins protect against coronary heart disease is supported, but it cannot be excluded that foods rich in these micronutrients also contain other constituents that provide the protection. Expand
Whole-grain and fiber intake and the incidence of type 2 diabetes.
TLDR
An inverse association between whole-grain intake and the risk of type 2 diabetes was found and the similar result for cereal fiber intake suggests that the whole- grain association is due to cereal fiber or another factor related to cereal Fiber intake. Expand
Dietary patterns and the incidence of type 2 diabetes.
TLDR
It appears conceivable that the risk of developing type 2 diabetes can be reduced by changing dietary patterns, and the prudent dietary pattern score was associated with a reduced risk and the conservative pattern scores were associated with an increased risk of type 1 diabetes. Expand
Dietary flavonoids and the risk of lung cancer and other malignant neoplasms.
TLDR
The association between flavonoid intake and lung cancer incidence was not due to the intake of antioxidant vitamins or other potential confounding factors, as adjustment for factors such as smoking and intakes of energy, vitamin E, vitamin C, and beta-carotene did not materially alter the results. Expand
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