• Publications
  • Influence
Human African trypanosomiasis of the CNS: current issues and challenges.
  • P. Kennedy
  • Biology, Medicine
  • The Journal of clinical investigation
  • 15 February 2004
Human African trypanosomiasis (HAT), also known as sleeping sickness, is a major cause of mortality and morbidity in sub-Saharan Africa. Current therapy with melarsoprol for CNS HAT has unacceptableExpand
  • 283
  • 29
  • PDF
The neurotropic herpes viruses: herpes simplex and varicella-zoster
Herpes simplex viruses types 1 and 2 (HSV1 and HSV2) and varicella-zoster virus (VZV) establish latent infection in dorsal root ganglia for the entire life of the host. From this reservoir they canExpand
  • 377
  • 24
Clinical features, diagnosis, and treatment of human African trypanosomiasis (sleeping sickness)
  • P. Kennedy
  • Biology, Medicine
  • The Lancet Neurology
  • 1 February 2013
Human African trypanosomiasis, or sleeping sickness, is caused by infection with parasites of the genus Trypanosoma, transmitted by the tsetse fly. The disease has two forms, Trypanosoma brucei (T b)Expand
  • 278
  • 20
The continuing problem of human African trypanosomiasis (sleeping sickness)
  • P. Kennedy
  • Biology, Medicine
  • Annals of neurology
  • 1 August 2008
Human African trypanosomiasis, also known as sleeping sickness, is a neglected disease, and it continues to pose a major threat to 60 million people in 36 countries in sub‐Saharan Africa. TransmittedExpand
  • 189
  • 16
  • PDF
Inflammatory demyelinating peripheral neuropathies associated with human T‐cell lymphotropic virus type III infection
Nine patients with inflammatory demyelinating polyneuropathies (IDP) were found to have human T‐cell lymphotropic virus type III (HTLV‐III) infection. The 8 men, 6 of whom were homosexual, and 1Expand
  • 325
  • 12
Diagnosis and treatment of viral encephalitis
Acute encephalitis constitutes a medical emergency. In most cases, the presence of focal neurological signs and focal seizures will distinguish encephalitis from encephalopathy. Acute disseminatedExpand
  • 197
  • 12
  • PDF
VIRAL ENCEPHALITIS: CAUSES, DIFFERENTIAL DIAGNOSIS, AND MANAGEMENT
  • P. Kennedy
  • Medicine
  • Journal of Neurology, Neurosurgery & Psychiatry
  • 20 February 2004
Encephalitis refers to an acute, usually diffuse, inflammatory process affecting the brain. While meningitis is primarily an infection of the meninges, a combined meningoencephalitis may also occur.Expand
  • 204
  • 11
  • PDF
Viral meningoencephalitis: a review of diagnostic methods and guidelines for management
Background:  Viral encephalitis is a medical emergency. The prognosis depends mainly on the pathogen and host immunologic state. Correct immediate diagnosis and introduction of symptomatic andExpand
  • 190
  • 11
  • PDF
Varicella-Zoster Virus Gene Expression in Latently Infected and Explanted Human Ganglia
ABSTRACT A consistent feature of varicella-zoster virus (VZV) latency is the restricted pattern of viral gene expression in human ganglionic tissues. To understand further the significance of thisExpand
  • 141
  • 10
  • PDF
Viral encephalitis: a review of diagnostic methods and guidelines for management
Viral encephalitis is a medical emergency. The spectrum of brain involvement and the prognosis are dependent mainly on the specific pathogen and the immunological state of the host. Although specificExpand
  • 182
  • 9
  • PDF