• Publications
  • Influence
Glutathione modulation influences methyl mercury induced neurotoxicity in primary cell cultures of neurons and astrocytes.
Methyl mercury (MeHg) is highly neurotoxic and may lead to numerous neurodegenerative disorders. In this study, we investigated the role of glutathione (GSH) and reactive oxygen species (ROS) inExpand
  • 176
  • 10
  • PDF
Trace Element Profiles in Single Strands of Human Hair Determined by HR-ICP-MS
Trace element analysis of human hair has the potential to reveal retrospective information about an individual’s nutritional status and exposure. As trace elements are incorporated into the hairExpand
  • 74
  • 3
  • PDF
Role of glutathione in determining the differential sensitivity between the cortical and cerebellar regions towards mercury-induced oxidative stress.
Certain discrete areas of the CNS exhibit enhanced sensitivity towards MeHg. To determine whether GSH is responsible for this particular sensitivity, we investigated its role in MeHg-inducedExpand
  • 59
  • 3
Uptake and efflux of methylmercury in vitro: comparison of transport mechanisms in C6, B35 and RBE4 cells.
Methylmercury (MeHg) is a neurotoxicant which enters the brain and may cause permanent change. Thus, the properties of MeHg transport across cell membranes are a key factor in designing anExpand
  • 35
  • 3
Docosahexaenoic acid may act as a neuroprotector for methylmercury-induced neurotoxicity in primary neural cell cultures.
The ability of docosahexaenoic acid (DHA) to modulate methylmercury (MeHg)-induced neurotoxicity was investigated in primary astrocytes and neurons from the cerebellum. Gas chromatographyExpand
  • 40
  • 2
Role of docosahexaenoic acid in modulating methylmercury-induced neurotoxicity.
The effect of docosahexaenoic acid (DHA) in modulating methylmercury (MeHg)-induced neurotoxicity was investigated in C6-glial and B35-neuronal cell lines. Gas chromatography measurements indicatedExpand
  • 28
  • 2
  • PDF
The use of fluorescence for detecting MeHg-induced ROS in cell cultures.
The effect of methylmercury (MeHg) on reactive oxygen species (ROS) induction in neural cell lines was measured by the fluorescent probe, chloro methyl derivative of di-chloro di-hydroExpand
  • 19
  • 2
Tellurium-induced dose-dependent impairment of antioxidant status
The effect of various doses of sodium tellurite (0.4, 0.8, and 2.0 mg/kg body weight, orally) on the activity of antioxidant enzymes (glutathione peroxidase, glutathione reductase,Expand
  • 12
  • 2
Dose- and duration-dependent alterations by tellurium on lipid levels
The effect of various doses of sodium tellurite (1/50 LD50=0.4 mg/kg, 1/25 LD50=0.8 mg/kg, and 1/10 LD50=2.0 mg/kg body weight orally) on the lipid levels (cholesterol, triglycerides, phospholipids,Expand
  • 8
  • 2
The in vitro effects of Trolox on methylmercury-induced neurotoxicity.
Methylmercury (MeHg), an environmental toxicant primarily found in fish and seafood poses a dilemma to both consumers and regulatory authorities given the nutritional benefits of fish consumption vs.Expand
  • 27
  • 1