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Overlap Syndrome of Asthma and COPD Predicts Low Quality of Life
Background. In clinical practice, patients whose airway disease shares features of both asthma and chronic obstructive pulmonary disease (COPD) remain poorly recognized. Material and methods. TheExpand
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A second-generation association study of the 5q31 cytokine gene cluster and the interleukin-4 receptor in asthma.
We have analyzed a dense set of single-nucleotide polymorphisms (SNPs) and microsatellites spanning the T-helper cytokine gene cluster (interleukins 3, 4, 5, 9, and 13, interferon regulatoryExpand
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Allergic rhinitis alone or with asthma is associated with an increased risk of sickness absences.
The aim of the study is to examine the risk of sickness absence in public sector employees with allergic rhinitis or asthma or both conditions combined. This is a prospective cohort study of 48,296Expand
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Are high‐ and low‐molecular‐weight sensitizing agents associated with different clinical phenotypes of occupational asthma?
High‐molecular‐weight (HMW) proteins and low‐molecular‐weight (LMW) chemicals can cause occupational asthma (OA) although few studies have thoroughly compared the clinical, physiological, andExpand
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Systemic inflammatory responses following welding inhalation challenge test
Aim The aim of this study was to investigate inflammatory and respiratory responses to welding fume exposure in patients with suspected occupational asthma. Methods Sixteen patients referred to theExpand
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Need for medication and stuffy nose predict the severity of allergic rhinitis
To the Editor, As a part of the Finnish Allergy Programme 2008-2018 [1], we surveyed patients to assess allergic rhinitis symptoms, the use of medications and health care services in Finland. Expand
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Birch pollen allergen immunotherapy reprograms nasal epithelial transcriptome and recovers microbial diversity.
Nasal epithelial transcriptome is altered by the season. Birch pollen allergen immunotherapy recovers microbial community diversity and alters expression of allergy related genes.
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Emerging Comorbidities in Adult Asthma: Risks, Clinical Associations, and Mechanisms
Asthma is a heterogeneous disease with many phenotypes, and age at disease onset is an important factor in separating the phenotypes. Most studies with asthma have been performed in patients beingExpand
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Verification of self-reported asthma and allergy in subjects and their family members volunteering for gene mapping studies.
Studies which aim at mapping genes contributing to the development of asthma and atopy demand that hundreds of patients and their family members be assessed. In Finland, the Social InsuranceExpand
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Drug allergy passport and other documentation for patients with drug hypersensitivity – An ENDA/EAACI Drug Allergy Interest Group Position Paper
The strongest and best‐documented risk factor for drug hypersensitivity (DH) is the history of a previous reaction. Accidental exposures to drugs may lead to severe or even fatal reactions inExpand
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