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Molecular Identification of a Malaria Merozoite Surface Sheddase
Proteolytic shedding of surface proteins during invasion by apicomplexan parasites is a widespread phenomenon, thought to represent a mechanism by which the parasites disengage adhesin-receptorExpand
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Toxoplasma gondii protease TgSUB1 is required for cell surface processing of micronemal adhesive complexes and efficient adhesion of tachyzoites
Host cell invasion by Toxoplasma gondii is critically dependent upon adhesive proteins secreted from the micronemes. Proteolytic trimming of microneme contents occurs rapidly after their secretionExpand
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Platelet-derived growth factor induces interleukin-1 receptor gene expression in Balb/c 3T3 fibroblasts.
Our previous studies have demonstrated that platelet-derived growth factor (PDGF) modulated cellular responses to interleukin-1 (IL-1). In this communication, we show that PDGF regulates expressionExpand
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Molecular Determinants for Subcellular Trafficking of the Malarial Sheddase PfSUB2
The malaria merozoite invades erythrocytes in the vertebrate host. Iterative rounds of asexual intraerythrocytic replication result in disease. Proteases play pivotal roles in erythrocyte invasion,Expand
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Identification of dioxin-responsive genes in Hep G2 cells using differential mRNA display RT-PCR.
Differential mRNA display RT-PCR (DD RT-PCR) offers a tool to identify genes which are regulated or responsive to certain receptors or chemicals such as dioxin (TCDD). Treatment of Hep G2 cells withExpand
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