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Reciprocal limbic-cortical function and negative mood: converging PET findings in depression and normal sadness.
OBJECTIVE Theories of human behavior from Plato to Freud have repeatedly emphasized links between emotion and reason, a relationship now commonly attributed to pathways connecting phylogeneticallyExpand
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Regional metabolic effects of fluoxetine in major depression: serial changes and relationship to clinical response
BACKGROUND Treatment of major depression with antidepressants is generally associated with a delay in onset of clinical response. Functional brain correlates of this phenomenon have not beenExpand
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A PET study of the neural systems of stuttering
THE cause of stuttering is unknown1. Failure to develop left-hemispheric dominance for speech is a long-standing theory1 although others implicate the motor system more broadly2, often postulatingExpand
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Cingulate function in depression: a potential predictor of treatment response
THE relationship between pretreatment regional cerebral glucose metabolism and eventual antidepressant drug response was measured using positron emission tomography (PET) in hospitalized patientsExpand
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Use of implicit motor imagery for visual shape discrimination as revealed by PET
POSITRON emission tomography (PET) can be used to map brain regions that are active when a visual object (for example, a hand) is discriminated from its mirror form. Chronometric studies1á\[euro]-3Expand
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Imaging human intra‐cerebral connectivity by PET during TMS
NON-INVASIVE imaging of human inter-regional neural connectivity by positron emission tomography (PET) during transcranial magnetic stimulation (TMS) was performed. The hand area of primary motorExpand
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The functional neuroanatomy of the placebo effect.
OBJECTIVE Administration of placebo can result in a clinical response indistinguishable from that seen with active antidepressant treatment. Functional brain correlates of this phenomenon have notExpand
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Frontostriatal disorder of cerebral metabolism in never-medicated schizophrenics.
We scanned 18 patients with schizophrenia who had never received neuroleptic medication and 20 age- and sex-matched controls by positron emission tomography with 18-F-fluorodeoxyglucoseExpand
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Intersubject Variability in Cortical Activations during a Complex Language Task
Intersubject variability in the functional organization of the human brain has theoretical and practical importance for basic and clinical neuroscience. In the present study, positron emissionExpand
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Non-invasive quantification of cerebral blood flow for rats by microPET imaging of 15O labelled water: the application of a cardiac time–activity curve for the tracer arterial input function
ObjectiveIn-vivo quantitative cerebral blood flow (CBF) measurement using positron emission tomography (PET) has typically employed invasive arterial blood sampling procedure to determine theExpand
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