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Whole-genome resequencing reveals loci under selection during chicken domestication
TLDR
The use of massively parallel sequencing is described to identify selective sweeps of favourable alleles and candidate mutations that have had a prominent role in the domestication of chickens and their subsequent specialization into broiler (meat- producing) and layer (egg-producing) chickens.
The twofold difference in adult size between the red junglefowl and White Leghorn chickens is largely explained by a limited number of QTLs.
TLDR
A large intercross between the domestic White Leghorn chicken and the wild ancestor, the red junglefowl, has been used in a Quantitative Trait Loci (QTL) study of growth and egg production, and the estimated effects all indicated a codominant inheritance.
Melanocortin 1-receptor (MC1R) mutations are associated with plumage colour in chicken.
TLDR
The results provided compelling evidence that the Extended black (E) locus controlling plumage colour is equivalent to MC1R, and E/MC1R was assigned to chromosome 11 with overwhelming statistical support.
A global search reveals epistatic interaction between QTL for early growth in the chicken.
TLDR
Very few loci affected the entire growth process, which points out that early and late growth, at least to some extent, have different genetic regulation.
Identification of the Yellow Skin Gene Reveals a Hybrid Origin of the Domestic Chicken
TLDR
Surprisingly, the results demonstrate that yellow skin does not originate from the red junglefowl, the presumed sole wild ancestor of the domestic chicken, but most likely from the closely related grey Junglefowl (Gallus sonneratii).
Gene expression across mammalian organ development
TLDR
It is found that the breadth of gene expression and the extent of purifying selection gradually decrease during development, whereas the amount of positive selection and expression of new genes increase during development.
Major Growth QTLs in Fowl Are Related to Fearful Behavior: Possible Genetic Links Between Fear Responses and Production Traits in a Red Junglefowl × White Leghorn Intercross
TLDR
Study of fear responses and their relation to production traits in red junglefowl, White Leghorn, and their F2-progeny shows that loci affecting important production traits are located in the same chromosomal region as loci affect different fear-related behaviors.
Single locus typing of MHC class I and class II B loci in a population of red jungle fowl
TLDR
This is the first time that a population of red jungle fowl has been typed at the MHC region, laying the basis for further research into the underlying processes acting to maintain MHC diversity in this and other species.
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