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Subcutaneous panniculitis-like T-cell lymphoma: definition, classification, and prognostic factors: an EORTC Cutaneous Lymphoma Group Study of 83 cases.
In the WHO classification, subcutaneous panniculitis-like T-cell lymphoma (SPTL) is defined as a distinct type of T-cell lymphoma with an aggressive clinical behavior. Recent studies suggest that… Expand
Reclassification of 300 primary cutaneous B-Cell lymphomas according to the new WHO-EORTC classification for cutaneous lymphomas: comparison with previous classifications and identification of…
- Nancy J. Senff, J. Hoefnagel, +10 authors R. Willemze
- Journal of clinical oncology : official journal…
- 20 April 2007
PURPOSE In the new WHO-European Organisation for Research and Treatment of Cancer (WHO-EORTC) classification for cutaneous lymphomas three major groups of primary cutaneous B-cell lymphoma (CBCL) are… Expand
Peripheral T-cell lymphomas unspecified presenting in the skin: analysis of prognostic factors in a group of 82 patients.
In the present study the clinicopathologic and immunophenotypic features of 82 patients with a CD30- peripheral T-cell lymphoma, unspecified, presenting in the skin were evaluated. The purpose of… Expand
CD56+ hematological neoplasms presenting in the skin: a retrospective analysis of 23 new cases and 130 cases from the literature.
- M. Bekkenk, P. Jansen, C. Meijer, R. Willemze
- Annals of oncology : official journal of the…
- 1 July 2004
BACKGROUND The aim of this study was to define prognostic parameters and guidelines for diagnosis and treatment for CD56+ hematological neoplasms with first presentation in the skin. PATIENTS AND… Expand
Effect of a recombinant dimeric tumor necrosis factor receptor on inflammatory responses to intravenous endotoxin in normal humans.
To determine the role of tumor necrosis factor (TNF) in lipopolysaccharide (LPS)-induced inflammation, 12 healthy subjects received an intravenous injection with LPS (2 ng/kg) preceded by infusion of… Expand
Bcl‐2, Bcl‐6 and CD10 expression in cutaneous B‐cell lymphoma: further support for a follicle centre cell origin and differential diagnostic significance
- J. Hoefnagel, M. Vermeer, P. Jansen, G. J. Fleuren, C. Meijer, R. Willemze
- The British journal of dermatology
- 1 December 2003
Background Primary cutaneous follicle centre cell lymphomas (PCFCCLs) are the most common type of cutaneous B‐cell lymphoma. There is ongoing discussion on the origin of the neoplastic B cells in… Expand
Expression of Programmed Death-1 in Primary Cutaneous CD4-Positive Small/Medium-Sized Pleomorphic T-Cell Lymphoma, Cutaneous Pseudo-T-Cell Lymphoma, and Other Types of Cutaneous T-Cell Lymphoma
- F. Çetinözman, P. Jansen, R. Willemze
- The American journal of surgical pathology
- 1 January 2012
In this study we investigated whether programmed death-1 (PD-1) could serve as a useful diagnostic marker to differentiate between primary cutaneous CD4+ small/medium-sized pleomorphic T-cell… Expand
Primary cutaneous marginal zone B-cell lymphoma: clinical and therapeutic features in 50 cases.
BACKGROUND Primary cutaneous marginal zone B-cell lymphoma (PCMZL) is a low-grade B-cell lymphoma that originates in the skin, with no evidence of extracutaneous disease. Studies focusing on the… Expand
Distinct types of primary cutaneous large B-cell lymphoma identified by gene expression profiling.
In the European Organization for Research and Treatment of Cancer (EORTC) classification 2 types of primary cutaneous large B-cell lymphoma (PCLBCL) are distinguished: primary cutaneous follicle… Expand
Prognostic factors in transformed mycosis fungoides: a retrospective analysis of 100 cases.
Large cell transformation (LCT) in mycosis fungoides (MF) is generally associated with an aggressive clinical course and poor survival, requiring aggressive therapeutic approach. However, a… Expand