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A common evolutionary origin for mitochondria and hydrogenosomes.
TLDR
P phylogenetic analyses of hydrogenosomal Hsp70, Hsp60, and Hsp10 show that these proteins branch within a monophyletic group composed exclusively of mitochondrial homologues, establishing that mitochondria and hydrogenosomes have a common eubacterial ancestor and imply that the earliest-branching eukaryotes contained the endosymbiont that gave rise to mitochondria in higher eukARYotes.
Trends in ixodid tick abundance and distribution in Great Britain
TLDR
The survey indicated that people perceive there to be more ticks today than in the past at 73% of locations throughout Britain, and the current known distribution of Ixodes ricinus Linnaeus (Acari: Ixodidae) has expanded by 17% in comparison with the previously known distribution.
Transient and selectable transformation of the parasitic protist Trichomonas vaginalis.
TLDR
The system the authors established to obtain selectable transformants uses the neomycin phosphotransferase (neo) gene as the selectable marker and shows that CAT activity is undetectable using TLC by 99 hr postelectroporation.
Regulation by the autophosphorylation site in overexpressed pp60c-src
TLDR
It is shown that overexpressed pp60c-src is phosphorylated at Tyr-416 and has increased specific kinase activity when isolated from cells incubated with vanadate, a tyrosine phosphatase inhibitor, and mutagenesis indicates that Tyr- 416 modulates pp60v-src activity as well.
Induction by E1A oncogene expression of cellular susceptibility to lysis by TNF
TLDR
Using an in vitro cytotoxicity assay with NIH 3T3 and Fisher BRK-derived cells expressing exogenously introduced oncogenes, it is found that adenovirus E1A proteins induce susceptibility to TNF killing.
Molecular analysis of the hydrogenosomal ferredoxin of the anaerobic protist Trichomonas vaginalis.
TLDR
The primary structure of the T. vaginalis ferredoxin of the anaerobic protist Trichomonas vaginalis shows the closest similarity to [2Fe-2S]putidared toxin of the aerobic bacterium Pseudomonas putida and a lesser one to mitochondria-based ferredoxins of vertebrates.
Overexpressed pp60c-src can induce focus formation without complete transformation of NIH 3T3 cells
TLDR
Results suggest that pp60v-src induced transformation is not a completely spurious activity which is unrelated to the function of pp60c-src but that it represents a perturbation of already existent molecular control processes involving pp60C-src.
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