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Engineered antibody fragments and the rise of single domains
With 18 monoclonal antibody (mAb) products currently on the market and more than 100 in clinical trials, it is clear that engineered antibodies have come of age as biopharmaceuticals. In fact, byExpand
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Deletion mapping and expression in Escherichia coli of the large genomic segment of a birnavirus.
The large genomic segment of infectious bursal disease virus encodes a polyprotein in which the viral polypeptides are present in the following order: N-VP2-VP4-VP3-C. Expression in Escherichia coliExpand
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Genomic structure of the large RNA segment of infectious bursal disease virus.
The larger RNA segment of infectious bursal disease virus (IBDV: Australian strain 002-73) has been characterized by cDNA cloning and nucleotide sequence analysis. We believe IBDV is the firstExpand
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The ecology of wildlife diseases
1: Ecology of wildlife diseases. 2: Heterogeneities in macroparasite infections: patterns and processes. 3: Parasites and host population dynamics. 4: Parasite community ecology and biodiversity. 5:Expand
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Genomic structure of tbe large RNA segment of infectious bursal disease virus
Abstract The larger RNA segment of infectious bursal disease virus (IBDV: Australian strain 002-73) has been characterized by cDNA cloning and nucleotide sequence analysis. We believe IBDV is theExpand
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Empirical evidence for key hosts in persistence of a tick-borne disease.
An important epidemiological consequence of aggregated host-parasite associations occurs when parasites are vectors of pathogens. Those hosts that attract many vectors will tend to be the focus ofExpand
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Understanding the net effects of pesticides on amphibian trematode infections.
Anthropogenic factors can have simultaneous positive and negative effects on parasite transmission, and thus it is important to quantify their net effects on disease risk. Net effects will be aExpand
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Prevention of population cycles by parasite removal.
The regular cyclic fluctuations in vertebrate numbers have intrigued scientists for more than 70 years, and yet the cause of such cycles has not been clearly demonstrated. Red grouse populations inExpand
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Do parasites make prey vulnerable to predation? Red grouse and parasites
An extensive post-mortem survey of grouse revealed that birds killed by predators in spring and summer had significantly greater burdens of the caecal nematode Trichostrongylus tenuis than grouseExpand
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Epidemic Dynamics at the Human-Animal Interface
Zeroing in on Zoonoses Influenza, plague, and Lyme disease are classic examples of zoonoses—diseases that circulate in livestock and wildlife, as well as in humans. When a pathogen transfers amongExpand
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