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A novel human prostate-specific, androgen-regulated homeobox gene (NKX3.1) that maps to 8p21, a region frequently deleted in prostate cancer.
Northern blot analyses indicate that this gene is expressed at high levels in adult prostate and at a much lower level in testis, but is expressed little or not at all in several other tissues, and it is proposed that NKX3.1 is a candidate gene for playing a role in the opposing processes of androgen-driven differentiation of prostatic tissue and loss of that differentiation during the progression of prostate cancer.
The expression of transthyretin mRNA in the developing rat brain.
Localization of insulin-like growth factor-I mRNA in rat brain by in situ hybridization--relationship to IGF-I receptors.
Recent evidence has demonstrated regional synthesis of insulin-like growth factor I (IGF-I) in rat brain, which is also known to contain widespread specific type I IGF receptors. In order to…
Structure and expression of the rat transthyretin (prealbumin) gene.
Synthesis of transthyretin (pre-albumin) mRNA in choroid plexus epithelial cells, localized by in situ hybridization in rat brain.
- A. Stauder, P. Dickson, A. Aldred, G. Schreiber, F. Mendelsohn, P. Hudson
- Biology, ChemistryThe journal of histochemistry and cytochemistry…
- 1 July 1986
The results indicate that substantial synthesis of transthyretin and transferrin mRNA may occur in the choroid plexus, and this synthesis may occur mainly in the lateral ventricles.
Regulation of proenkephalin gene expression by angiotensin in bovine adrenal medullary cells: Molecular mechanisms and nature of the second messenger systems
DNA methylation within the I.4 promoter region correlates with CYPl19A1 gene expression in human ex vivo mature omental and subcutaneous adipocytes
Increasing DNA methylation was correlated with aromatase mRNA expression and thus estradiol biosynthesis in mature adipocytes, supporting a tissue-specific epigenetic regulation of the basal promoter activity in maturity adipocytes.
Molecular cloning and characterization of ovine homeo-box-containing genes.