P. Heering

Publications62
h-index19
Citations1,464
Highly Influential Citations43
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A phase 1, single-dose study of fresolimumab, an anti-TGF-β antibody, in treatment-resistant primary focal segmental glomerulosclerosis
Primary focal segmental glomerulosclerosis (FSGS) is a disease with poor prognosis and high unmet therapeutic need. Here, we evaluated the safety and pharmacokinetics of single-dose infusions of… Expand
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Cyclosporin in idiopathic glomerular disease associated with the nephrotic syndrome : workshop recommendations.
Management of idiopathic glomerular disease associated with nephrotic syndrome (INS) remains controversial and one of the most complex areas relates to utilization of the drug cyclosporin. This is… Expand
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Cytokine removal and cardiovascular hemodynamics in septic patients with continuous venovenous hemofiltration
Objectives: To determine whether continuous venovenous hemofiltration leads to extraction of tumor necrosis factor alpha (TNFα) and cytokines from the circulation of critically ill patients with… Expand
  • 235
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Cardiovascular risk factors and diseases after renal transplantation
Cardiovascular disease is a leading cause of death after renal tranpslantation (tpx), and the incidence is considerably higher than in the general population.ObjectiveTo evaluate the incidence of… Expand
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Reduced incidence of acute renal graft failure in patients treated with peritoneal dialysis compared with hemodialysis.
In a case-control study performed in two centers, the incidence of delayed graft function (DGF), defined as the necessity to perform dialysis after transplantation, was analyzed according to prior… Expand
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Systemic mycophenolate mofetil in comparison with systemic cyclosporin A in high-risk keratoplasty patients: 3 years' results of a randomized prospective clinical trial
Abstract. Background: With the use of systemic cyclosporin A (CsA), graft prognosis after high-risk penetrating keratoplasty has improved considerably. However, the application of CsA is limited… Expand
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The "point of no return" and the rate of progression in the natural history of IgA nephritis.
BACKGROUND Based on the observation of 7 patients with chronic IgA nephritis and on a course to end-stage renal failure after several years, D'Amico et al. [1993] reported on a "point of no return"… Expand
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Effect of flosulide, a selective cyclooxygenase 2 inhibitor, on passive heymann nephritis in the rat.
BACKGROUND Nonsteroidal anti-inflammatory drugs (NSAIDs) induce an inhibition of cyclooxygenase (COX), an enzyme that makes prostaglandins. Two isoforms of COX exist: COX-1 represents the… Expand
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Systemic ciclosporin A in high-risk keratoplasties
Abstract• Background: It was the purpose of this study to compile the results of all high-risk keratoplasties (kp) performed in our hospital under systemic ciclosporin A (Ci A) cover from 1987… Expand
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Comparison of a lactate-versus acetate-based hemofiltration replacement fluid in patients with acute renal failure.
The objective of the study was to determine the impact of a lactate- and an acetate-based hemofiltration replacement fluid (HF) on the acid-base status in patients with acute renal failure (ARF) and… Expand
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