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Postoperative radiotherapy in high-risk premenopausal women with breast cancer who receive adjuvant chemotherapy. Danish Breast Cancer Cooperative Group 82b Trial.
- M. Overgaard, P. Hansen, +8 authors K. Zedeler
- The New England journal of medicine
- 2 October 1997
BACKGROUND Irradiation after mastectomy can reduce locoregional recurrences in women with breast cancer, but whether it prolongs survival remains controversial. We conducted a randomized trial of… Expand
Alpha-cardiac actin is a novel disease gene in familial hypertrophic cardiomyopathy.
We identified the alpha-cardiac actin gene (ACTC) as a novel disease gene in a pedigree suffering from familial hypertrophic cardiomyopathy (FHC). Linkage analyses excluded all the previously… Expand
The apolipoprotein E polymorphism in Greenland Inuit in its global perspective
- L. Gerdes, C. Gerdes, P. Hansen, I. Klausen, O. Faergeman, J. Dyerberg
- Biology, Medicine
- Human Genetics
- 26 September 1996
Abstract Apolipoprotein E (apoE) genotypes were determined in Inuit population samples from Nuuk on the south-west coast of Greenland (n = 100) and from the Ammassalik region on the south-east coast… Expand
α-cardiac actin is a novel disease gene in familial hypertrophic cardiomyopathy
: We identified the alpha-cardiac actin gene (ACTC) as a novel disease gene in a pedigree suffering from familial hypertrophic cardiomyopathy (FHC). Linkage analyses excluded all the previously… Expand
Detection of the apoB-3500 mutation (glutamine for arginine) by gene amplification and cleavage with MspI.
- P. Hansen, N. Rüdiger, A. Tybjaerg-Hansen, O. Faergeman, N. Gregersen
- Biology, Medicine
- Journal of lipid research
- 1 July 1991
A single primer-template mismatch 2 bp from the apoB-3500 (G to A) mutation permits introduction of a cleavage site for MspI (C/CGG) in normal alleles but not in mutant alleles (CCAG). After… Expand
Sequential Versus Simultaneous Biventricular Resynchronization for Severe Heart Failure: Evaluation by Tissue Doppler Imaging
Background—Cardiac resynchronization therapy (CRT) by means of simultaneous biventricular pacing improves left ventricular systolic performance and synchrony in patients with heart failure and… Expand
Radiofrequency Ablation as Initial Therapy in Paroxysmal Atrial Fibrillation
*Department of Cardiology, Aarhus University Hospital, Aarhus; and †Gentofte University Hospital, Copenhagen, Denmark; ‡Heart Center, Tampere University Hospital, Tampere, Finland; §Leipzig… Expand
Exaggeration of nonculprit stenosis severity during acute myocardial infarction: implications for immediate multivessel revascularization.
- C. Hanratty, Y. Koyama, H. Rasmussen, G. C. Nelson, P. Hansen, M. Ward
- Journal of the American College of Cardiology
- 4 September 2002
OBJECTIVES This study was designed to assess the prevalence and clinical significance of exaggerated nonculprit lesion stenosis in the setting of acute (<12 h) myocardial infarction (AMI). … Expand
Impact of Substrate Modification by Catheter Ablation on Implantable Cardioverter–Defibrillator Interventions in Patients With Unstable Ventricular Arrhythmias and Coronary Artery Disease: Results…
- K. Kuck, R. Tilz, +7 authors S. Willems
- Circulation. Arrhythmia and electrophysiology
- 1 March 2017
Background— The implantable cardioverter–defibrillator (ICD) is the standard therapy to prevent sudden cardiac death in patients with coronary artery disease and unstable ventricular… Expand
Are men carrying the apolipoprotein ε4- or ε2 allele less fertile than ε3ε3 genotypes?
The ɛ3 allele in the human gene coding for apolipoprotein E (apoE) is the most common worldwide, but ɛ4 is probably the ancestral allele. Since apoE is involved in many important biological… Expand