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Zeros of sampled systems
The zeros of the discrete time system obtained when sampling a continuous time system are explored. Theorems for the limiting zeros for large and small sampling periods are given. A condition whichExpand
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Zeros of sampled systems
The zeros of the discrete time system obtained when sampling a continuous time system are explored. Theorems for the limiting zeros for large and small sampling periods are given. A condition whichExpand
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A new design of constrained controllers for linear systems
A new method is presented to find stabilizing saturated linear state feedback controllers for linear continuous-time and discrete-time systems. A controller of this type was satisfactorily tested onExpand
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Avoiding acetate accumulation in Escherichia coli cultures using feedback control of glucose feeding.
An automated glucose feeding strategy that avoids acetate accumulation in cultivations of Escherichia coli is discussed. We have previously described how a probing technique makes it possible toExpand
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A FEEDBACK SCHEDULER FOR REAL-TIME CONTROLLER TASKS
The problem studied in this paper is how to distribute computing resources over a set of realtime control loops in order to optimize the total control performance. Two subproblems are investigated:Expand
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On-line detection of acetate formation in Escherichia coli cultures using dissolved oxygen responses to feed transients.
Recombinant protein production in Escherichia coli can be significantly reduced by acetate accumulation. It is demonstrated that acetate production can be detected on-line with a standard dissolvedExpand
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A new design of constrained controllers for linear systems
A new method is presented to find stabilizing saturated linear state feedback controllers for linear continuous-time and discrete-time systems. A controller of this type was satisfactorily tested onExpand
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Production of heterologous thermostable glycoside hydrolases and the presence of host-cell proteases in substrate limited fed-batch cultures of Escherichia coli BL21(DE3)
Abstract. Metabolic stress is a phenomenon often discussed in conjunction with recombinant protein production in Escherichia coli. This investigation shows how heterologous protein production and theExpand
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Experience in using an ethanol sensor to control molasses feed-rates in baker's yeast production
An ethanol sensor has been tested for feed-rate control of baker's yeast prouction. The yeast was grown on molasses in an 8 dm3 fed-batch reactor up to a cell concentration of 60–70 kg/m3. StudiesExpand
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Probing control of fed-batch cultivations: analysis and tuning
Production of various proteins can today be made using genetically modified Escherichia coli bacteria. In cultivations of E. coli it is important to avoid accumulation of the by-product acetate.Expand
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