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Abnormal Cerebral Structure Is Present at Term in Premature Infants
Background. Long-term studies of the outcome of very prematurely born infants have clearly documented that the majority of such infants have significant motor, cognitive, and behavioral deficits.… Expand
Mapping the early cortical folding process in the preterm newborn brain.
In the developing human brain, the cortical sulci formation is a complex process starting from 14 weeks of gestation onward. The potential influence of underlying mechanisms (genetic, epigenetic,… Expand
Early Alteration of Structural and Functional Brain Development in Premature Infants Born with Intrauterine Growth Restriction
Placental insufficiency with fetal intrauterine growth restriction (IUGR) is an important cause of perinatal mortality and morbidity and is subsequently associated with significant neurodevelopmental… Expand
Diffusion tensor imaging of brain development.
Understanding early human brain development is of great clinical importance, as many neurological and neurobehavioral disorders have their origin in early structural and functional cerebral… Expand
Primary cortical folding in the human newborn: an early marker of later functional development.
In the human brain, the morphology of cortical gyri and sulci is complex and variable among individuals, and it may reflect pathological functioning with specific abnormalities observed in certain… Expand
Perinatal Exposure to Bisphenol A Alters Early Adipogenesis in the Rat
- E. Somm, V. Schwitzgebel, +5 authors P. Hüppi
- Medicine, Biology
- Environmental health perspectives
- 29 June 2009
Background The causes of the current obesity pandemic have not been fully elucidated. Implication of environmental endocrine disruptors such as bisphenol A (BPA) on adipose tissue development has… Expand
Quantitative magnetic resonance imaging of brain development in premature and mature newborns
Definition in the living premature infant of the anatomical and temporal characteristics of development of critical brain structures is crucial for insight into the time of greatest vulnerability of… Expand
Imaging biomarkers of outcome in the developing preterm brain
The neurodevelopmental disabilities of those who were born prematurely have been well described, yet the underlying alterations in brain development that lead to these changes remain poorly… Expand
Diffusion tensor imaging of normal and injured developing human brain ‐ a technical review
The application of diffusion tensor imaging (DTI) to the evaluation of developing brain remains an area of active investigation. This review focuses on the changes in DTI parameters which accompany… Expand
Clinical proton MR spectroscopy in central nervous system disorders.
A large body of published work shows that proton (hydrogen 1 [(1)H]) magnetic resonance (MR) spectroscopy has evolved from a research tool into a clinical neuroimaging modality. Herein, the authors… Expand