• Publications
  • Influence
Characterization of nerve growth factor receptor in neural crest tumors using monoclonal antibodies.
The nerve growth factor (NGF) receptor was characterized by using a new series of anti-receptor monoclonal antibodies (MAbs). These MAbs (i) showed significantly greater reactivity with a melanomaExpand
  • 279
  • 10
  • PDF
Proposed regulatory pathway encoded by the nodV and nodW genes, determinants of host specificity in Bradyrhizobium japonicum.
Bradyrhizobium japonicum is the root nodule endosymbiont of soybean (Glycine max), mung bean (Vigna radiata), cowpea (Vigna unguiculata), and Siratro (Macroptilium atropurpureum). We report theExpand
  • 139
  • 7
Structures of three distinct activator-TFIID complexes.
Sequence-specific DNA-binding activators, key regulators of gene expression, stimulate transcription in part by targeting the core promoter recognition TFIID complex and aiding in its recruitment toExpand
  • 66
  • 5
BAC-VAC, a novel generation of (DNA) vaccines: A bacterial artificial chromosome (BAC) containing a replication-competent, packaging-defective virus genome induces protective immunity against herpes
  • M. Suter, A. Lew, +4 authors C. Fraefel
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 26 October 1999
This study aimed to exploit bacterial artificial chromosomes (BAC) as large antigen-capacity DNA vaccines (BAC-VAC) against complex pathogens, such as herpes simplex virus 1 (HSV-1). The 152-kbpExpand
  • 72
  • 4
  • PDF
Glia cell response to bacterial lipopolysaccharide: Effect on nucleotide synthesis, its genetic control and definition of the active principle
Cell types sensitive to lipopolysaccharides (LPS) include macrophages, polymorphonuclear leukocytes, platelets, B-lymphocytes and fibroblasts. Earlier observations that during endotoxemia orExpand
  • 13
  • 2
In vitro binding of the Salmonella dublin virulence plasmid regulatory protein SpvR to the promoter regions of spvA and spvR.
The spv regulon of Salmonella dublin is essential for virulence in mice. SpvR, a LysR-type regulator, induces the expression of the spvABCD operon and its own expression in the stationary phase ofExpand
  • 49
  • 2
In vitro stimulation of glia cells by a lymphocyteproduced factor
The factors responsible for the activation of astrocytes surrounding inflammatory brain tissues are unknown. The present study was designed to examine the ability of lymphocytes to produce astrocyteExpand
  • 74
  • 1
Indirect immobilization of recombinant proteins to a solid phase using the albumin binding domain of streptococcal protein G and immobilized albumin.
Immobilization of proteins to a solid phase leads to denaturation of the adsorbed molecules which may subsequently affect biological interactions. However, for many applications maintenance of theExpand
  • 23
  • 1