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Frequent chronic hepatitis B virus infection in HIV-infected patients positive for antibody to hepatitis B core antigen only
Persons with immune deficiency may present with atypical results in serological tests for hepatitis B virus (HBV). Frozen serum specimens that were sequentially obtained over time from a cohort of 57Expand
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Change in circulating levels of the chemokines macrophage inflammatory proteins 1α and 1β, RANTES, monocyte chemotactic protein‐1 and interleukin‐16 following treatment of severely immunodeficient
Objective:To evaluate the in vivo relationship between HIV replication and circulating levels of the chemokines macrophage inflammatory protein (MIP)-1α, MIP-1β, RANTES (acronym for Regulated uponExpand
  • 80
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Borderline low thyroid function and thyroid autoimmunity. Risk factors for coronary heart disease?
Assessments were made of 945 consecutive hospital patients with regard to a relation between borderline low thyroid function (recognised by a slightly raised thyroid stimulating hormone), thyroidExpand
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Polyvalent immunoglobulins for prophylaxis of bacterial infections in patients following multiple trauma
One hundred and fifty severely injured patients requiring long-term artificial ventilation were evaluated in a prospective, randomized, double blind study comparing the prophylactic effect of anExpand
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Immunological abnormalities and HLA antigen frequencies in IgA deficient patients with epilepsy.
Twenty-three epileptics with constitutional factors for seizures and low IgA serum concentrations were studied. Imbalance of the IgG subclasses was often observed, the IgG4 being undetectable in 13Expand
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Simple monitoring of antiretroviral therapy with a signal‐amplification‐boosted HIV‐1 p24 antigen assay with heat‐denatured plasma
Objective:Virus load determination has become indispensable for the management of HIV patients, but depends on expensive assays of a low throughput. We evaluated whether a highly improved HIV-1 p24Expand
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Highly active antiretroviral therapy during early HIV infection reverses T‐cell activation and maturation abnormalities
Objectives:To evaluate the impact of early initiation of highly active antiretroviral therapy (HAART) on disease-induced T-cell activation and maturation abnormalities during asymptomatic HIVExpand
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Highly active antiretroviral therapy during early HIV infection reverses T-cell activation and maturation abnormalities. Swiss HIV Cohort Study.
OBJECTIVES To evaluate the impact of early initiation of highly active antiretroviral therapy (HAART) on disease-induced T-cell activation and maturation abnormalities during asymptomatic HIVExpand
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Altered intracellular expression of the chemokines MIP‐1α, MIP‐1β and IL‐8 by peripheral blood CD4+ and CD8+ T cells in mild allergic asthma
Background: The ability of chemokines to regulate Th1 and Th2 responses suggests a role in the pathogenesis of atopic disorders such as allergic asthma where Th2 response dominance has been observed.Expand
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Hepatitis B: virus, pathogenesis and treatment.
  • P. Grob
  • Biology, Medicine
  • Vaccine
  • 1 November 1998
The hepatitis B virus (HBV) is a coated, incompletely double-stranded DNA virus with some outstanding features. (1) All three coat proteins of HBV contain HBsAg, which is highly immunogenic inducingExpand
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