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Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine.
BACKGROUND Calcitonin gene-related peptide (CGRP) may have a causative role in migraine. We therefore hypothesized that a CGRP-receptor antagonist might be effective in the treatment of migraineExpand
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New Appendix Criteria Open for a Broader Concept of Chronic Migraine
After the introduction of chronic migraine and medication overuse headache as diagnostic entities in The International Classification of Headache Disorders, Second Edition, ICHD-2, it has been shownExpand
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EFNS guidelines on the treatment of cluster headache and other trigeminal‐autonomic cephalalgias
Cluster headache and the other trigeminal‐autonomic cephalalgias [paroxysmal hemicrania, short‐lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT)Expand
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Triptans (Serotonin, 5-HT1B/1D Agonists) in Migraine: Detailed Results and Methods of A Meta-Analysis of 53 Trials
The triptans, selective serotonin 5-HT1B/1D agonists, are very effective acute migraine drugs. Soon, seven different triptans will be clinically available at 13 different oral doses, makingExpand
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Cluster headache: A prospective clinical study with diagnostic implications
BackgroundCluster headache, when compared with migraine or tension-type headache, is an uncommon form of primary neurovascular headache. However, with a prevalence of approximately 0.1% and a lengthyExpand
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A Controlled Trial of Erenumab for Episodic Migraine
BACKGROUND We tested erenumab, a fully human monoclonal antibody that inhibits the calcitonin gene–related peptide receptor, for the prevention of episodic migraine. METHODS We randomly assignedExpand
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The International Classification of Headache Disorders: 2nd edition
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Pathophysiology of cluster headache: a trigeminal autonomic cephalgia
  • P. Goadsby
  • Medicine
  • The Lancet Neurology
  • 1 August 2002
Cluster headache is a form of primary neurovascular headache with the following features: severe unilateral, commonly retro-orbital, pain accompanied by restlessness or agitation, and cranialExpand
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Correlation between structural and functional changes in brain in an idiopathic headache syndrome
Fundamental to the concept of idiopathic or primary headache, including migraine, tension-type headache and cluster headache, is the currently accepted view that these conditions are due to abnormalExpand
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EFNS guideline on the drug treatment of migraine – revised report of an EFNS task force
Background:  Migraine is one of the most frequent disabling neurological conditions with a major impact on the patients’ quality of life.
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