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Aripiprazole Attenuates the Discriminative-Stimulus and Subject-Rated Effects of D-Amphetamine in Humans
The results of animal research suggest that the use of partial agonists at dopamine (DA) D2 receptors may be an effective strategy for the treatment of stimulant dependence. Aripiprazole is anExpand
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Radiocarbon evidence for the substrates supporting methane formation within northern Minnesota peatlands
Bogs and fens from northern Minnesota produce large quantities of CH4, which may be either emitted to the atmosphere or stored in below-ground reservoirs. The identity of the organic materials thatExpand
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A low dose of aripiprazole attenuates the subject-rated effects of d-amphetamine.
Despite increased reports of amphetamine abuse and dependence, a putative pharmacotherapy has yet to be identified. In a previous study from our laboratory, 20 mg aripiprazole, an atypicalExpand
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Atomoxetine Treatment of Attention-Deficit/Hyperactivity Disorder in Young Adults With Assessment of Functional Outcomes: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Background Attention-deficit/hyperactivity disorder (ADHD) is associated with significant impairment in multiple functional domains. This trial evaluated efficacy in ADHD symptoms and functionalExpand
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Reinforcing effects of modafinil: influence of dose and behavioral demands following drug administration
RationaleThe reinforcing effects of stimulant drugs are modulated by behavioral demands following drug administration.ObjectiveThe objective of this study was to assess the reinforcing effects ofExpand
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The spontaneously hypertensive and Wistar Kyoto rat models of ADHD exhibit sub-regional differences in dopamine release and uptake in the striatum and nucleus accumbens
The most widely used animal model of attention-deficit/hyperactivity disorder (ADHD) is the spontaneously hypertensive rat (SHR/NCrl), which best represents the combined subtype (ADHD-C). RecentExpand
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Methylphenidate increases cigarette smoking in participants with ADHD
RationaleMethylphenidate (Ritalin®) is commonly prescribed for behavioral problems associated with attention deficit/hyperactivity disorder (ADHD). The results of previous studies suggest thatExpand
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Risperidone Attenuates the Discriminative-Stimulus Effects of d-Amphetamine in Humans
Studies conducted with nonhuman laboratory animals have consistently shown that atypical antipsychotics that are mixed dopamine and serotonin antagonists attenuate the discriminative-stimulus effectsExpand
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Reinforcing, subject-rated, performance and physiological effects of methylphenidate and d-amphetamine in stimulant abusing humans
Methylphenidate has potential for abuse because it produces behavioural effects similar to those observed with other abused stimulants, such as d-amphetamine and cocaine. The aim of this study was toExpand
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Alprazolam Attenuates the Behavioral Effects of d-Amphetamine in Humans
Abstract: The results of preclinical behavioral pharmacology studies suggest that γ-aminobutyric acidA (GABAA) receptor modulators attenuate the behavioral effects of commonly abused stimulants suchExpand
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