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Mesophilic crenarchaeota: proposal for a third archaeal phylum, the Thaumarchaeota
TLDR
It is shown that these mesophilic archaea are different from hyperthermophilic Crenarchaeota and branch deeper than was previously assumed, and should be considered as a third archaeal phylum, which the authors propose to name Thaum archaeota. Expand
An atypical topoisomerase II from archaea with implications for meiotic recombination
TLDR
It is suggested that Spo11 catalyses the formation of double-strand breaks that initiate meiotic recombination in S. cerevisiae by analogy with the mechanism of action of known type II topoisomerases. Expand
The virophage as a unique parasite of the giant mimivirus
TLDR
The Sputnik genome is an 18.343-kilobase circular double-stranded DNA and contains genes that are linked to viruses infecting each of the three domains of life Eukarya, Archaea and Bacteria and is classified as a virophage. Expand
Viruses of the Archaea: a unifying view
TLDR
A unifying view on archaeal viruses is provided, and they are presented as a particular assemblage that is fundamentally different in morphotype and genome from the DNA viruses of the other two domains of life, the Bacteria and Eukarya. Expand
Origin and evolution of DNA topoisomerases.
TLDR
The main characteristics of the different families and subfamilies of DNA topoisomerases are reviewed in a historical and evolutionary perspective, with the hope to stimulate further works and discussions on the origin and evolution of these fascinating enzymes. Expand
An Alternative Flavin-Dependent Mechanism for Thymidylate Synthesis
TLDR
It is shown that ThyX (Thy1) proteins of previously unknown function form a large and distinct class of thymidylate synthases, which present a previously uncharacterized target for antimicrobial compounds. Expand
The Rooting of the Universal Tree of Life Is Not Reliable
TLDR
All composite protein trees used to root the universal tree of life with updated data sets are revisited and it is suggested that an eukaryotic rooting could be a more fruitful working hypothesis, as it provides a simple explanation to the high genetic similarity of Archaebacteria and Eubacteria inferred from complete genome analysis. Expand
Phylogeny and evolution of the Archaea: one hundred genomes later.
TLDR
Analysis provides an increasingly complex picture of archaeal phylogeny and evolution with the proposal of new major phyla, such as the Thaumarchaeota, and important information on the evolution of key central cellular features such as cell division. Expand
Nanoarchaea: representatives of a novel archaeal phylum or a fast-evolving euryarchaeal lineage related to Thermococcales?
TLDR
It is indicated that the placement of N. equitans in archaeal phylogenies on the basis of ribosomal protein concatenation may be strongly biased by the coupled effect of its above-average evolutionary rate and lateral gene transfers. Expand
Redefining viruses: lessons from Mimivirus
TLDR
A new definition for a virus is proposed — a capsid-encoding organism that is composed of proteins and nucleic acids, self-assembles in a nucleocapsid and uses a ribosome-encoded organism for the completion of its life cycle. Expand
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