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Chromerid genomes reveal the evolutionary path from photosynthetic algae to obligate intracellular parasites
Insight is provided into how obligate parasites with diverse life strategies arose from a once free-living phototrophic marine alga, and co-regulated with genes encoding the flagellar apparatus supporting the functional contribution of flagella to the evolution of invasion machinery.
Ancient genomes document multiple waves of migration in Southeast Asian prehistory
Ancient migrations in Southeast Asia The past movements and peopling of Southeast Asia have been poorly represented in ancient DNA studies (see the Perspective by Bellwood). Lipson et al. generated…
Re-evaluating the Green versus Red Signal in Eukaryotes with Secondary Plastid of Red Algal Origin
The impact of EGT on eukaryote genomes is evaluated by reanalyzing the recently published EST dataset for Chromera velia, an interesting test case of a photosynthetic alga closely related to apicomplexan parasites, which reveals the lack of congruence and the subjectivity resulting from independent phylogenomic screens for EGT.
The Streamlined Genome of Phytomonas spp. Relative to Human Pathogenic Kinetoplastids Reveals a Parasite Tailored for Plants
Comparison with other trypanosomatid genomes revealed a highly streamlined genome, encoding for a minimized metabolic system while conserving the major pathways, and with retention of a full complement of endomembrane organelles, but with no evidence for functional complexity.
Divergent mitochondrial respiratory chains in phototrophic relatives of apicomplexan parasites.
It is shown that the respiratory chain of Chromera velia, a phototrophic relative of parasitic apicomplexans, lacks complexes I and III, making it a uniquely reduced aerobic mitochondrion.
Split photosystem protein, linear-mapping topology, and growth of structural complexity in the plastid genome of Chromera velia.
massive genomic coverage by paired-end reads, coupled with pulsed-field gel electrophoresis and polymerase chain reaction, consistently indicate that the C. velia plastid genome is linear-mapping, a unique state among all plastids.
Paleo-Eskimo genetic ancestry and the peopling of Chukotka and North America
A comprehensive model for the Holocene peopling events of Chukotka and North America is developed, and it is shown that Na-Dene-speaking peoples, people of the Aleutian Islands, and Yup’ik and Inuit across the Arctic region all share ancestry from a single Palaeo-Eskimo-related Siberian source.
The genetic history of admixture across inner Eurasia
Genome-wide data for 763 individuals from inner Eurasia reveal 3 admixture clines in present-day populations that mirror geography, illuminating the historic spread and mixture of peoples across the Eurasian steppe, taiga and tundra.
Paratrypanosoma Is a Novel Early-Branching Trypanosomatid
Leptomonas seymouri: Adaptations to the Dixenous Life Cycle Analyzed by Genome Sequencing, Transcriptome Profiling and Co-infection with Leishmania donovani
It is demonstrated that L. seymouri is well adapted for the environment of the warm-blooded host and remains a predominantly monoxenous species not capable of infecting vertebrate cells under normal conditions.