P. Fernandes

Publications116
h-index28
Citations2,164
Highly Influential Citations76
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Antinociceptive activity of Amazonian Copaiba oils.
Copaiba oil resins are extensively commercialized in Brazil as capsules or crude oil and used as anti-inflammatory and anti-septic. Comparative pharmacological studies between different species of… Expand
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In vivo and in vitro studies on the anticancer activity of Copaifera multijuga hayne and its fractions
Copaiba oil resin (COR) obtained from Copaifera multijuga Hayne has been used in popular medicine as an antinflammatory and for the treatment of bronchitis, ulcers and cancer. The aim of this study… Expand
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Anti-Inflammatory Properties and Chemical Characterization of the Essential Oils of Four Citrus Species
Citrus fruits have potential health-promoting properties and their essential oils have long been used in several applications. Due to biological effects described to some citrus species in this study… Expand
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Isatins inhibit cyclooxygenase-2 and inducible nitric oxide synthase in a mouse macrophage cell line.
Isatin is a versatile compound with a diversity of effects. We designed to investigate the inhibitory effect of isatin derivatives on lipopolysaccharide/interferon-gamma-induced expression of… Expand
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A selective cyclooxygenase-2 inhibitor suppresses the growth of endometriosis with an antiangiogenic effect in a rat model.
OBJECTIVE To analyze the antiangiogenic effects of the selective cyclooxygenase-2 (COX-2) inhibitor parecoxib on the growth of endometrial implants in a rat model of peritoneal endometriosis. … Expand
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Role of nitric oxide and superoxide in Giardia lamblia killing.
Giardia lamblia trophozoites were incubated for 2 h with activated murine macrophages, nitric oxide (NO) donors or a superoxide anion generator (20 mU/ml xanthine oxidase plus 1 mM xanthine).… Expand
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Investigation of anti-inflammatory and antinociceptive activities of Lantana trifolia.
The anti-inflammatory activity of Lantana trifolia (Verbenaceae) was determined by carrageenan, serotonin and histamine-induced rat paw edema and the analgesic activity of this plant was studied by… Expand
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Flavones and phenylpropanoids from a sedative extract of Lantana trifolia L.
The flavone glycosides, named scutellarein-7-O-beta-D-apiofuranoside and apigenin-7-O-beta-D-apiofuranosyl-(1-->2)-beta-D-apiofuranoside, and the flavone celtidifoline… Expand
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Platelet-activating factor receptor (PAF-R)-dependent pathways control tumour growth and tumour response to chemotherapy
BackgroundPhagocytosis of apoptotic cells by macrophages induces a suppressor phenotype. Previous data from our group suggested that this occurs via Platelet-activating factor receptor… Expand
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Natural regeneration of Pinus pinaster and Eucalyptus globulus from plantation into adjacent natural habitats
Abstract The tree species used in planted forests are highly productive and have an important role in countries economy but the expansion of these trees into habitats outside plantations is a concern… Expand
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