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Transforming growth factor-beta-related proteins: an ancestral and widespread superfamily of cytokines in metazoans.
TLDR
Analysis of the large diversity of ligands, receptors and Smads in metazoans from cnidarians and molluscs to mammals shows that TGF-betas are probably the most ancestral active cytokines characterized at the molecular level in both Protostome and Deuterostome lineages.
Characterization of a Defensin from the Oyster Crassostrea gigas
TLDR
The results suggest that Cg-def gene is continuously expressed in the mantle and would play a key role in oyster by providing a first line of defense against pathogen colonization.
DNA Methylation Is Crucial for the Early Development in the Oyster C. gigas
TLDR
It is demonstrated that DNA methylation influences gene expression in Crassostrea gigas and is critical for oyster development, possibly by specifically controlling the transcription level of homeobox orthologues.
Generation and analysis of a 29,745 unique Expressed Sequence Tags from the Pacific oyster (Crassostrea gigas) assembled into a publicly accessible database: the GigasDatabase
TLDR
A publicly-available database has been populated with 29,745 unique sequences for the Pacific oyster Crassostrea gigas, one of the most developed genomic resources accessible among Lophotrochozoans, an orphan clade of bilateral animals.
Increasing genomic information in bivalves through new EST collections in four species: development of new genetic markers for environmental studies and genome evolution.
TLDR
This paper presents the analysis of the 13,013 expressed sequence tags (ESTs) generated, which form the basis for subsequent microarray design, SNP detection and polymorphism analysis, and the placement of novel markers on genetic linkage maps.
Effects of different vertebrate growth factors on primary cultures of hemocytes from the gastropod mollusc, Haliotis tuberculata.
TLDR
The response of primary cultures of abalone hemocytes to vertebrate growth factors confirms their growth potential in vitro and provides a suitable model for further studies on regulation of the control of cellular processes such as cell growth, differentiation and migration in invertebrate cells.
Characterization of an atypical family 18 chitinase from the oyster Crassostrea gigas: evidence for a role in early development and immunity.
TLDR
Gene expression profiles monitored by quantitative RT-PCR in different adult tissues and during development support for the first time the involvement of a singular chitinase homologue from the bivalve mollusc Crassostrea gigas in early embryonic development, suggesting that Cg-Chit plays an important role as an immunity effector in molluscs.
Molecular cloning of a molluscan gonadotropin-releasing hormone receptor orthologue specifically expressed in the gonad.
TLDR
Quantitative RT-PCR shows a specific expression of Cg-GnRH-R in both male and female gonads during the reproductive cycle, demonstrating for the first time the plausible involvement of a GnRH receptor orthologue in the control of reproduction in a protostomian invertebrate.
Characterization of GnRH-related peptides from the Pacific oyster Crassostrea gigas
TLDR
This study characterized two GnRH-related peptides by mass spectrometry from extracts of the visceral ganglia of the Pacific oyster Crassostrea gigas, suggesting the involvement of Cg-GnRHs as synchronizers of nutritional status with energy requirements during reproduction in oyster and evidence for a role of Cgs as neuroregulators and as neuroendocrine factors in bivalve is discussed.
Gametogenesis in the Pacific Oyster Crassostrea gigas: A Microarrays-Based Analysis Identifies Sex and Stage Specific Genes
TLDR
This study allowed us to identify potential markers of early sex differentiation in the oyster C. gigas, an alternative hermaphrodite mollusk and provided new highly valuable information on genes specifically expressed by mature spermatozoids and mature oocytes.
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