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Attenuation of p53 Expression Protects against Focal Ischemic Damage in Transgenic Mice
TLDR
The data suggest that attenuated p53 expression may be protective after an ischemic event, and that grater protection was afforded by reduced expression of p53.
The nature and timing of excitotoxic neuronal necrosis in the cerebral cortex, hippocampus and thalamus due to flurothyl-induced status epilepticus
TLDR
The results showed that acidophilic neurons appeared simultaneously in neurons of the neocortex, hippocampus and thalamus, and that this occurred within 1 h following the end of the epilepsy, which supports an excitotoxic mechanism in epilepsy-induced selective neuronal necrosis also in brain regions outside the hippocampus.
Ontogenetic Profile of the Adenosine Uptake Sites in Rat Forebrain
TLDR
The ontogenetic profile of [3H]CHA appears to coincide with synaptogenesis whereas that of [2H]NBI does not, and the binding of [ 3H?]NBI in 6‐day‐old tissue to be indistinguishable from such binding in 30‐day-old tissue.
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