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Effect of number of suckling pups and dietary calcium on bone mineral content and mechanical properties of femurs of lactating rats.
It is concluded that the change in Ca homeostasis in lactating rats is due to the large loss ofCa required for milk production and that the loss of Ca is associated with hyperfunction of the parathyroid gland. Expand
Increase in serum parathyroid hormone concentration in the lactating rat: Effects of dietary calcium and lactational intensity
The data demonstrate that lactation in the rat is characterized by hyperparathyroidism that appears to be related to lactational intensity and that is accentuated when dietary calcium intake is restricted and suggests that parathyroid hormone plays a role in the bone loss normally seen in lactating rats. Expand
Parathyroid hormone and plasma calcium control: an editorial.
The purpose of this report is to examine the various processes by which parathyroid hormone might control the ionic calcium concentration of plasma and extracellular fluid, and to emphasize the needExpand
It was found that cutting, stretching or burning the recurrent laryngeal nerves resulted in respiratory difficulty and retarded the fall in serum calcium after parathyroidectomy—results similar to those produced by thyroparathyroid surgery. Expand
Influence of lactation and pregnancy + lactation on mechanical properties and mineral content of the rat femur
  • T. Peng, Robert P. Kusy, Sanford C. Garner, P. F. Hirsch, Maria C. De Blanco
  • Biology, Medicine
  • Journal of bone and mineral research : the…
  • 1 June 1987
The quality of bone was assessed from femurs of rats both during lactation and after pregnancy + lactation, and changes, especially stiffness and strength, were relatively larger than the changes in dry and ash weights of bone, which provide a more sensitive method to evaluate the quality ofBone. Expand
Thyrocalcitonin inhibition of bone resorption induced by parathyroid extract in thyroparathyroidectomized rats.
The results indicate that thyrocalcitonin inhibited the release of calcium from both “stable” and “labile” bone, but that the inhibition was more marked in unlabeled bone, presumably the same area of bone that was responsive to parathyroid hormone. Expand
A scanning electron microscopic and photon absorptiometric study of the development, prolongation, and pattern of recovery from lactation‐induced osteopenia in Rats
The results demonstrate the marked loss of bone during lactation, especially severe in rats fed a low‐calcium diet, and the rapid postlactational recovery of bone when adequate dietary calcium was made available, even if the recovery had been delayed for the first 3 weeks by feeding a diet very low in calcium. Expand
Cytochemical bioassay of circulating concentrations of rat parathyroid hormone: Application to a study of age and sex
The cytochemical bioassay method, originally developed to measure circulating levels of biologically active parathyroid hormone (bioPTH) in humans, also can measure endogenous concentrations of PTH in rats, and the concentration of bioPTH increased in both males and females from 5 to 15 months of age. Expand
Influence of ethanol on stiffness, toughness, and ductility of femurs of rats.
The results confirm that the femurs of rats fed an ethanol liquid diet for 4 weeks are not only weaker but also more compliant and less energy absorbing and the bones are more prone to fracture in fatigue and impact circumstances as well as under simple loading situations. Expand
Calcitonin, an enigmatic hormone: does it have a function?
This editorial presents the view of the status of thyroidal calcitonin (TCT) in mammalian physiology and concerns three possibilities with respect to TCT: the hormone is vestigial; the hormone plays a role in water metabolism, ionic concentrations, and/or acid-base balance, actions that may not involve calcium metabolism at all; and the hormone acts to store phosphate postprandially on bone surfaces. Expand