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High-dose recombinant tumor necrosis factor alpha in combination with interferon gamma and melphalan in isolation perfusion of the limbs for melanoma and sarcoma.
PURPOSE To determine the toxicity and the therapeutic efficacy of the combination of the recombinant tumor necrosis factor alpha (rTNF alpha), recombinant interferon gamma (rIFN-gamma), andExpand
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Single-beat estimation of right ventricular end-systolic pressure-volume relationship.
Assessment of right ventricular (RV) contractility from end-systolic pressure-volume relationships (ESPVR) is difficult due to problems in measuring RV instantaneous volume and to effects of changesExpand
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Effects of norepinephrine and dobutamine on pressure load-induced right ventricular failure*
ObjectiveA transient increase in pulmonary arterial (PA) pressure can persistently depress right ventricular (RV) contractility. We investigated the effects norepinephrine and dobutamine on RV-PAExpand
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Antimicrobial prophylaxis for major head and neck surgery in cancer patients: sulbactam-ampicillin versus clindamycin-amikacin.
A total of 99 patients with head and neck cancer who were to undergo surgery were randomized in a prospective comparative study of sulbactam-ampicillin (1:2 ratio; four doses of 3 g of ampicillin andExpand
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Results of 206 isolated limb perfusions for malignant melanoma.
Between 1976 and 1988, 182 patients--135 females (74.3%) and 47 males (25.7%)--were submitted to 206 isolation perfusions, using melphalan and mild hyperthermia for 34 upper and 172 lower limbs.Expand
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In transit metastases of malignant melanoma treated by high dose rTNF alpha in combination with interferon-gamma and melphalan in isolation perfusion.
To increase the therapeutic efficacy of recombinant tumor necrosis factor alpha (rTNF alpha) and reduce the systemic side effects, a protocol was designed using isolation perfusion of the limbs withExpand
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Alizapride in the prevention of post-thyroidectomy emetic sequelae
Two-hundred patients scheduled for elective thyroidectomy under halothane-nitrous-oxide-oxygen anaesthesia were randomly divided into two equal groups and were blindly given either alizapride 100 mgExpand
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Isoflurane and Desflurane Impair Right Ventricular–Pulmonary Arterial Coupling in Dogs
Background:Halogenated anesthetics depress left ventricular function, but their effects on the right ventricle have been less well studied. Therefore, the authors studied the effects of isofluraneExpand
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Intravenous tramadol compared to propacetamol for postoperative analgesia following thyroidectomy.
We compared the efficacy and side effects of propacetamol (P), an injectable prodrug of acetaminophen, 2 g and tramadol (T), a weak synthetic opioid, 1.5 mg.kg-1, given intravenously followingExpand
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Antiemetic effect of subhypnotic doses of propofol after thyroidectomy.
Postoperative nausea and vomiting (PONV) are unpleasant, often underestimated side effects of anaesthesia and surgery, not devoid of medical complications. Prevention with antiemetics is onlyExpand
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