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Pulmonary arterial hypertension in congenital heart disease: an epidemiologic perspective from a Dutch registry.
TLDR
PAH is common in adult patients with congenital heart disease and in the authors' registry the prevalence of PAH in septal defects is around 6%. Expand
The spectrum of adult congenital heart disease in Europe: morbidity and mortality in a 5 year follow-up period. The Euro Heart Survey on adult congenital heart disease.
TLDR
The spectrum of adult CHD in Europe emerging from this survey is one of a predominantly young population with substantial morbidity but relatively low mortality in a 5 year period. Expand
Pulmonary arterial hypertension in adults born with a heart septal defect: the Euro Heart Survey on adult congenital heart disease
TLDR
In this selected population of adults with congenital heart disease, PAH was common and predisposed to more symptoms and further clinical deterioration, even among patients with previous defect closure and patients who had not developed Eisenmenger’s physiology. Expand
Lifetime Medical Costs of Obesity: Prevention No Cure for Increasing Health Expenditure
TLDR
Although effective obesity prevention leads to a decrease in costs of obesity-related diseases, this decrease is offset by cost increases due to diseases unrelated to obesity in life-years gained. Expand
Aortic root growth in men and women with the Marfan's syndrome.
TLDR
By reducing the cut-off value for elective aortic root replacement in women with MS by 5 mm, type A dissections could have been prevented in 3 women, and guidelines should take gender differences into account, the investigators propose. Expand
Delivery of care for adult patients with congenital heart disease in Europe: results from the Euro Heart Survey.
TLDR
It is indicated that the provision of care in Europe for adults with congenital heart defects is suboptimal and continuous effort must be applied by healthcare professionals in order to implement the recommendations on the organization of care for these patients. Expand
Gender differences in adult congenital heart disease
TLDR
Evidence is found that gender differences exist in morbidity and mortality among adult patients with congenital heart disease, as well as in medical management among adults born with a heart defect. Expand
Cost-effectiveness of a low-calorie diet and orlistat for obese persons: modeling long-term health gains through prevention of obesity-related chronic diseases.
TLDR
It is recommended that a low-calorie diet should be the first option for policymakers in combating obesity and cost-effectiveness ratios of interventions aiming at weight reduction depend strongly on assumptions regarding the relation between BMI and quality of life. Expand
Beyond the root: dilatation of the distal aorta in Marfan’s syndrome
TLDR
Careful monitoring of the entire aorta is essential for the optimal management of patients with Marfan’s syndrome, especially after elective surgery, but is insufficiently performed in Europe. Expand
Importance of nondrug costs of intravenous antibiotic therapy
TLDR
Total costs of IV antibiotic administration are formed not only by the costs of the drugs themselves, but also, to a substantial degree, by the time expended by medical and nursing staff, costs of disposable materials and overhead costs. Expand
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