In vivo modulation of alternative pathways of P-450-catalyzed cyclophosphamide metabolism: impact on pharmacokinetics and antitumor activity.
- L. Yu, P. Drewes, K. Gustafsson, E. Brain, J. E. Hecht, D. Waxman
- Biology, ChemistryJournal of Pharmacology and Experimental…
- 1 March 1999
It is demonstrated that the P-4503A inhibitor TAO can be used to effectively modulate CPA metabolism and pharmacokinetics in vivo in a manner that decreases the formation of toxic metabolites that do not contribute to antitumor activity.
Corporate Social Responsibility in Maritime Logistics
- T. Pawlik, P. Gaffron, P. Drewes
- Business
- 12 January 2012
Abstract
This chapter discusses the concept of corporate social responsibility (CSR) within the context of the container liner shipping industry. It looks at the current practice of CSR in this…
Metabolism of fluoroacetic acid-2-C-14 in the intact rat.
- E. Gal, P. Drewes, N. F. Taylor
- BiologyArchives of Biochemistry and Biophysics
- 1 April 1961
Faster and easier radioimmunoassay of digoxin.
- P. Drewes, V. Pileggi
- BiologyClinical Chemistry
- 1 March 1974
We describe an improved radioimmunoassay method for serum digoxin, with 125I as tracer, to eliminate the problems that endanger the validity of this assay: apparent instability of tracer,…
Assimilative capacity of the Waccamaw River and the Atlantic Intracoastal Waterway near Myrtle Beach, South Carolina, 1989-92
- P. Drewes, P. Conrads
- Environmental Science
- 1995
Hydrologic and Water Quality Monitoring on Turkey Creek Watershed, Francis Marion National Forest, SC
- D. Amatya, T. Callahan, A. Radecki-Pawlik, P. Drewes, C. Trettin, W. Hansen
- Environmental Science
- 2008
The Turkey Creek watershed is a gauged 3rd order stream draining 7,260 ha on the US Forest Service Francis Marion National Forest and a portion of the adjoining Santee Experimental Forest. A stream…
Water Resources Data, South Carolina, Water Year 1998
- T. Cooney, P. Drewes, K. Jones, S. Ellisor, B. Church
- Environmental Science
- 1999
Water Resources Data, South Carolina, Water Year 1996
- T. Cooney, K. Jones, P. Drewes, J. W. Gissendanner, B. Church
- Environmental Science
- 1996
Studies on the Metabolism of 5-Hydroxytryptamine (Serotonin) II. Effect of Tryptophan Deficiency in Rats
Feeding of sulfasuxidine, presumably through its antibacterial action, led to greater recovery of intestinal serotonin in tryptophan-deficient rats, and injection of PIH resulted in a statistically significant increase of 5-HT in the blood but not in the brain of deficient animals.
Measurement of urinary aldosterone by a simplified radioimmunoassay procedure.
- P. Drewes, J. Demetriou, V. Pileggi
- BiologyClinical Biochemistry
- 1 March 1973
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