P. Doraiswamy

Publications420
h-index82
Citations23,515
Highly Influential Citations802
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Effects of exercise training on older patients with major depression.
TLDR
After 16 weeks of treatment exercise was equally effective in reducing depression among patients with MDD, and an exercise training program may be considered an alternative to antidepressants for treatment of depression in older persons.
Exercise and Pharmacotherapy in the Treatment of Major Depressive Disorder
TLDR
The efficacy of exercise in patients seems generally comparable with patients receiving antidepressant medication and both tend to be better than the placebo in patients with MDD.
Use of florbetapir-PET for imaging beta-amyloid pathology.
TLDR
Evidence is provided that a molecular imaging procedure can identify β-amyloid pathology in the brains of individuals during life and for the prediction of progression to dementia.
Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study
Cognitive Function in Late Life Depression: Relationships to Depression Severity, Cerebrovascular Risk Factors and Processing Speed
Using positron emission tomography and florbetapir F18 to image cortical amyloid in patients with mild cognitive impairment or dementia due to Alzheimer disease.
TLDR
The findings of this analysis confirm the ability of florbetapir-PET SUVRs to characterize amyloid levels in clinically probable AD, MCI, and OHC groups using continuous and binary measures of fibrillar Aβ burden.
Neuroimaging and early diagnosis of Alzheimer disease: a look to the future.
Alzheimer disease (AD), a progressive neurodegenerative disorder, is the most common cause of dementia in the elderly. Current consensus statements have emphasized the need for early recognition and…
Exercise and pharmacological treatment of depressive symptoms in patients with coronary heart disease: results from the UPBEAT (Understanding the Prognostic Benefits of Exercise and Antidepressant…
Hypercortisolemia and hippocampal changes in depression
Florbetapir (F18-AV-45) PET to assess amyloid burden in Alzheimer's disease dementia, mild cognitive impairment, and normal aging
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