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ESIMS analysis of fucoidan preparations from Costaria costata, extracted from alga at different life-stages.
It was confirmed, that monosaccharide content and structure of fucoidans of vegetative algae changed following its life stage.
Monanchocidin: a new apoptosis-inducing polycyclic guanidine alkaloid from the marine sponge Monanchora pulchra.
Compound 1 shows pro-apoptotic and cytoxic activities and the structure of 1 was assigned on the basis of detailed analysis of 1D and 2D NMR spectra, mass spectrometry, and results of chemical transformations.
Anticancer activity in vitro of a fucoidan from the brown alga Fucus evanescens and its low-molecular fragments, structurally characterized by tandem mass-spectrometry.
Fucoidan was isolated and purified from the brown algae Fucus evanescens and subjected to autohydrolysis to obtain low-molecular-weight fragments, which exhibited almost no action to cell proliferation in both cell lines and colony formation on SK- MEL-5 cells, but its inhibition activity to the colony formation of SK-MEL-28 cell lines was as high as was demonstrated by native fucoidan.
Structural analysis of a fucoidan from the brown alga Fucus evanescens by MALDI-TOF and tandem ESI mass spectrometry.
A fucoidan, a heterogeneous sulfated polysaccharide from the brown alga Fucus evanescens, was depolymerized under solvolytic conditions, and its ethanol-extracted low-molecular-weight fraction was
Monanchocidins B-E: polycyclic guanidine alkaloids with potent antileukemic activities from the sponge Monanchora pulchra.
Compounds 1-5 show potent cytotoxic activities against HL-60 human leukemia cells with IC50 values of 540, 200, 110, 830, and 650 nM, respectively.
Meroterpenoids from the alga-derived fungi Penicillium thomii Maire and Penicillium lividum Westling.
Ten new austalide meroterpenoids (1-10) were isolated from the alga-derived fungi and exhibited significant inhibitory activity against endo-1,3-β-D-glucanase from a crystalline stalk of the marine mollusk Pseudocardium sachalinensis.
Constituents of the sea cucumber Cucumaria okhotensis. Structures of okhotosides B1-B3 and cytotoxic activities of some glycosides from this species.
Three new triterpene oligoglycosides, okhotosides B 1, B 2, and B 3, have been isolated from the sea cucumber Cucumaria okhotensis and the structures of 1- 3 were elucidated on the basis of their spectroscopic data (2D NMR and MS).
New APETx-like peptides from sea anemone Heteractis crispa modulate ASIC1a channels
Electrophysiological experiments on homomeric ASIC channels expressed in Xenopus laevis oocytes establish that these peptides are the first inhibitors of ASIC1a derived from sea anemone venom.
Polysaccharide and lipid composition of the brown seaweed Laminaria gurjanovae
The fucoidan is suggested to be a highly sulfated partially acetylated galactofucan (Fuc/Gal is ∼1: 1), and the main lipid components of the dried L. gurjanovae are neutral lipids and glyceroglycolipids, whereas phospholipids are found in minor amounts.
Secondary metabolites from a marine-derived fungus Aspergillus carneus Blochwitz.
Prenylated indole alkaloids, carneamides A-C, quinazolinone derivatives, and a drimane sesquiterpenoid together with known compounds isolated from the marine-derived fungus Aspergillus carneus (Trichocomaceae) KMM 4638 were examined.