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Microwave-assisted one-pot synthesis of benzothiazole and benzoxazole libraries as analgesic agents
- C. Praveen, A. Nandakumar, P. Dheenkumar, D. Muralidharan, P. Perumal
- Journal of Chemical Sciences
- 9 June 2012
AbstractMicrowave-assisted synthesis of benzothiazole and benzoxazole libraries via PIFA promoted cyclocondensation of 2-aminothiophenols/2-aminophenols with aldehydes under one-pot condition in good… Expand
Solvent-free implementation of two dissimilar reactions using recyclable CuO nanoparticles under ball-milling conditions: synthesis of new oxindole-triazole pharmacophores
Herein, synthesis of new hybrid pharmocophores by merging Baylis–Hillman and click chemistry under ball-milling conditions was accomplished. The substrate scope of the reaction was broadened to… Expand
Synthesis, antimicrobial and antioxidant evaluation of quinolines and bis(indolyl)methanes.
- C. Praveen, P. Dheenkumar, D. Muralidharan, P. Perumal
- Chemistry, Medicine
- Bioorganic & medicinal chemistry letters
- 15 December 2010
An improved and practical synthesis of substituted quinolines and bis(indolyl)methanes was achieved under microwave condition using Zn(OTf)(2) as catalyst. The synthesized compounds have been… Expand
Zn(OTf)2-catalysed indolylation and pyrrolylation of isatins: Efficient synthesis and biochemical assay of 3,3-di(heteroaryl)oxindoles
- C. Praveen, S. Narendiran, P. Dheenkumar, P. Perumal
- Journal of Chemical Sciences
- 24 December 2013
AbstractAn efficient and cheap synthetic approach to 3,3-di(indolyl)oxindoles and 3,3-di(pyrrolyl)oxindoles has been developed via Zn(OTf)2 catalysed indolylation and pyrrolylation of isatins. A… Expand
Super acid catalysed sequential hydrolysis/cycloisomerization of o-(acetylenic)benzamides under microwave condition: Synthesis, antinociceptive and antiinflammatory activity of substituted…
AbstractSynthesis of isocoumarins and related compounds via triflic acid promoted hydrolysis/cyclization sequence of 2-(alkynyl)benzamides under microwave condition was achieved. The substrate scope… Expand
Solvent and catalyst free route to 3-indolyl glycoconjugates: synthesis of sugar tethered isoxazolines and isoxazoles from 3-indolyl nitroalkanes
An expedient, solvent and catalyst free strategy for the synthesis of sugar based bis(indolyl)methanes and indolyl nitroalkanes has been developed. The protocol works well within a wide range of… Expand
Microwave assisted synthesis of heterocyclic compounds and its Biological activity
- P. Dheenkumar
- 11 January 2012
Zn(OTf)2‐Catalyzed Indolylation and Pyrrolylation of Isatins: Efficient Synthesis and Biochemical Assay of 3,3‐Di(heteroaryl)oxindoles.
Super Acid Catalyzed Sequential Hydrolysis/Cycloisomerization of o‐(Acetylenic)benzamides under Microwave Condition: Synthesis, Antinociceptive and Antiinflammatory Activity of Substituted…
This is the first direct synthesis of isocoumarins from o-alkynylbenzamides under super acid conditions.
Synthesis, Antimicrobial and Antioxidant Evaluation of Quinolines and Bis(indolyl)methanes.
All synthesized compounds of type (III) exhibit good antimicrobial activities with (IIIe) being more active than the standard bis(indoyl)methanes (VIc) and (VId) show better activity than the… Expand