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Nasal CPAP or intubation at birth for very preterm infants.
TLDR
In infants born at 25-to-28-weeks' gestation, early nasal CPAP did not significantly reduce the rate of death or bronchopulmonary dysplasia, as compared with intubation, and fewer infants received oxygen at 28 days, and they had fewer days of ventilation. Expand
Caffeine therapy for apnea of prematurity.
TLDR
Caffeine therapy for apnea of prematurity reduces the rate of bronchopulmonary dysplasia in infants with very low birth weight and reduced weight gain temporarily. Expand
Prophylactic intravenous indomethacin for preventing mortality and morbidity in preterm infants.
TLDR
There is no evidence to suggest prophylactic indomethacin is associated with any reduction in long-term neurosensory impairment, ie no significant difference in rates of cognitive delay, cerebral palsy, blindness or deafness. Expand
Long-term effects of caffeine therapy for apnea of prematurity.
TLDR
Caffeine therapy for apnea of prematurity improves the rate of survival without neurodevelopmental disability at 18 to 21 months in infants with very low birth weight. Expand
Defining the Reference Range for Oxygen Saturation for Infants After Birth
TLDR
These data represent reference ranges for pulse oxygen saturation (Spo2) values in the first 10 minutes after birth for preterm and term infants. Expand
Impact of Postnatal Systemic Corticosteroids on Mortality and Cerebral Palsy in Preterm Infants: Effect Modification by Risk for Chronic Lung Disease
TLDR
The effect of postnatal corticosteroids on the combined outcome of death or CP varies with the level of risk for CLD, whereas with risks for ClD exceeding 65%, it reduced this chance. Expand
High-flow nasal cannulae in very preterm infants after extubation.
TLDR
Although the result for the primary outcome was close to the margin of noninferiority, the efficacy of high-flow nasal cannulae was similar to that of CPAP as respiratory support for very preterm infants after extubation. Expand
Breathing Patterns in Preterm and Term Infants Immediately After Birth
TLDR
Directly after birth, both preterm and term infants frequently brake their expiration, mostly by crying, and preterm infants use significantly more expiratory breath holds to defend their lung volume. Expand
Volume-targeted versus pressure-limited ventilation in the neonate.
TLDR
Although rates of death and BPD were not significantly different between the two ventilator strategies, statistically significant effects favouring volume targeting were shown for some clinically important outcomes. Expand
Prophylactic nasal continuous positive airway pressure for preventing morbidity and mortality in very preterm infants.
TLDR
To determine if prophylactic nasal CPAP started soon after birth regardless of respiratory status in the very preterm or very low birth weight infant reduces the use of IPPV and the incidence of bronchopulmonary dysplasia (BPD) without adverse effects, a meta-analysis was performed. Expand
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