• Publications
  • Influence
Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial
TLDR
Hydroxychloroquine treatment is significantly associated with viral load reduction/disappearance in COVID-19 patients and its effect is reinforced by azithromycin, which was significantly more efficient for virus elimination. Expand
Pig liver sausage as a source of hepatitis E virus transmission to humans.
TLDR
The findings strongly support the hypothesis of HEV infection through ingestion of raw figatellu, a traditional pig liver sausage widely eaten in France and commonly consumed raw, as a source ofHEV infection. Expand
rpoB-Based Identification of Nonpigmented and Late-Pigmenting Rapidly Growing Mycobacteria
TLDR
It is concluded that molecular identification by analysis of the 723-bp rpoB sequence is a rapid and accurate tool for identification of RGM. Expand
Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a six-day follow up: A pilot observational study
TLDR
There is urgency to evaluate the effectiveness of this potentially-life saving therapeutic strategy at a larger scale, both to treat and cure patients at an early stage before irreversible severe respiratory complications take hold and to decrease duration of carriage and avoid the spread of the disease. Expand
Transfusion-associated Hepatitis E, France
TLDR
The first case in France and the first case worldwide involving a child as blood recipient of HEV recently emerged as a transfusion-transmitted pathogen is described and HEV nucleotide sequences from the blood donor and recipient were identical. Expand
New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19?
TLDR
The possible mechanisms of chloroquine interference with the SARS-CoV-2 replication cycle are discussed, which could lead to new therapies able to counter the most severe effects of the disease. Expand
“Megavirales”, a proposed new order for eukaryotic nucleocytoplasmic large DNA viruses
TLDR
These characteristics lead us to propose assigning an official taxonomic rank to the NCLDVs as the order “Megavirales”, in reference to the large size of the virions and genomes of these viruses. Expand
Zamilon, a Novel Virophage with Mimiviridae Host Specificity
TLDR
By co-culturing amoebae with purified Zamilon, it is found that the virophage is able to multiply with members of groups B and C of the Mimiviridae family but not with viruses from group A. Expand
Chloroquine and hydroxychloroquine as available weapons to fight COVID-19
TLDR
The Covid-19 pandemic triggered, more frequently, anxiety, depression, stress and post-traumatic stress disorders in the general population and health professionals Women, students and nurses are among the most affected. Expand
Autochthonous Infections with Hepatitis E Virus Genotype 4, France
TLDR
HEV genotype 4, which is described almost exclusively in Asia, was recovered from 2 persons who ate uncooked pork liver sausage and genetic sequences were 96.7% identical to those recently described in swine in Europe. Expand
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