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Guidelines for diagnosis, prevention and treatment of hand eczema

Topical corticosteroids are recommended as first line treatment in the management of HE, however continuous long‐term treatment beyond six weeks only when necessary and under careful medical supervision is recommended.
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The epidemiology of occupational contact dermatitis

The lack of truly epidemiologic data on OCD and the difficulties of those studies are illustrated and the following issues are highlighted: case ascertainment and bias, the distribution of allergic and irritant contact dermatitis in the working population, the interrelationship between exogenous and endogenous factors, the prognosis, the social and economic impact, and the need for intervention studies.
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Efficacy and safety of oral alitretinoin (9‐cis retinoic acid) in patients with severe chronic hand eczema refractory to topical corticosteroids: results of a randomized, double‐blind,…

Background  Patients with severe chronic hand eczema (CHE) refractory to topical corticosteroids currently have limited treatment options suited for chronic use, and few controlled clinical studies…
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The European standard series in 9 European countries, 2002/2003 – First results of the European Surveillance System on Contact Allergies

Since January 2001, the European Surveillance System on Contact Allergies (ESSCA), supported by European Union funding (contract QLK4‐CT‐2001‐00343), has started to collect patch‐test data. This…
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Evaluation of a self‐administered questionnaire on hand dermatitis

It is concluded that the self‐reported diagnosis can be used to obtain a rough estimate of the prevalence, although comparison of prevalence figures between study populations may be distorted due to a difference in reporting of hand dermatitis.
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Oral alitretinoin (9-cis-retinoic acid) therapy for chronic hand dermatitis in patients refractory to standard therapy: results of a randomized, double-blind, placebo-controlled, multicenter trial.

Alitretinoin given at well-tolerated doses induced substantial clearing of chronic hand dermatitis in patients refractory to conventional therapy.
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Formaldehyde‐releasers: relationship to formaldehyde contact allergy. Contact allergy to formaldehyde and inventory of formaldehyde‐releasers

Formaldehyde and formaldehyde allergy are reviewed: applications, exposure scenarios, legislation, patch testing problems, frequency of sensitization, relevance of positive patch test reactions, clinical pattern of allergic contact dermatitis from formaldehyde, prognosis, threshold for elicitation of allergicContact dermatitis, analytical tests to determine formaldehyde in products and frequency of exposure to formaldehyde and releasers.
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The European baseline series in 10 European Countries, 2005/2006 – Results of the European Surveillance System on Contact Allergies (ESSCA)

Continual surveillance based on patch test results has proved useful for the identification of contact allergy and will continue to be a useful tool for this purpose.
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Management of chronic hand eczema

It is concluded that despite the abundance of topical and systemic treatment options, disease management in patients with severe chronic HE is frequently inadequate and there is a strong need for RCTs of existing and new treatment options based on clearly diagnosed subtypes of HE and its severity.
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Induction of atopic dermatitis by inhalation of house dust mite.

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