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Developmental Transcriptomic Features of the Carcinogenic Liver Fluke, Clonorchis sinensis
TLDR
The transcriptomic information on essential regulators of development, bile chemotaxis, and physico-metabolic pathways in C. sinensis that presented in this study will guide further studies to identify novel drug targets and diagnostic antigens. Expand
Current situation of scrub typhus in South Korea from 2001–2013
TLDR
A rapid increase in the incidence of patients with tsutsugamushi disease was observed in most areas from 2001 to 2013, with the majority of cases reported in the western and southern coast. Expand
Genetic diversity and natural selection of Duffy binding protein of Plasmodium vivax Korean isolates.
TLDR
The results suggest that PvDBPII of Korean P. vivax isolates display a limited genetic polymorphism and are under selective pressure, which has significant implications for understanding the nature of the P.vivax population circulating in Korea and useful information for development of malaria vaccines based on this antigen. Expand
Reference genes for quantitative analysis on Clonorchis sinensis gene expression by real-time PCR
TLDR
This work determined the gene expression stabilities of eight reference gene candidates and the relative transcript levels of three target genes using the geNorm program and proposed a method to employ the geometric mean of the CT values of more than three reference genes validated in the same experimental setting. Expand
Clonorchis sinensis: codon usage in nuclear genes.
TLDR
Codon usage in Clonorchis sinensis was analyzed and suggested that codon usage is shaped by a bias towards G or C at the third base, and that this is affected by the first and second bases. Expand
Prevalence of clonorchiasis in southern endemic areas of Korea in 2006.
TLDR
The present findings suggest that clonorchiasis is still highly prevalent among inhabitants in the riverside areas of southern Korea, and it is necessary to implement a systematic control program in the endemic areas. Expand
Hemolytic activity and developmental expression of pore-forming peptide, clonorin.
TLDR
It is proposed that, through lysing host cellular components, clonorin could enhance proteolytic digestion in the intestine of C. sinensis. Expand
MOLECULAR CLONING AND CHARACTERIZATION OF VITELLINE PRECURSOR PROTEIN B1 FROM CLONORCHIS SINENSIS
TLDR
The CsVpB1 cDNA is believed to encode a VpB of C. sinensis, and was found to be rich in tyrosine residues, including putative pre-dihydroxyphenyl alanine (DOPA) residues, involved in cross-linking of the precursor proteins. Expand
Epidemiological survey on the infection of intestinal flukes in residents of Muan-gun, Jeollanam-do, the Republic of Korea.
TLDR
It was confirmed that A. felis is a new intestinal fluke infecting humans, and residents in Muan-gun, Jeollanam-do are infected with variable species of intestinal trematodes. Expand
Anthelmintic activity of KSI-4088 against Caenorhabditis elegans
TLDR
KSI-4088 is an active anthelmintic compound that should be further investigated with the aim of developing a potent drug against nematodes, and it is demonstrated that C. elegans L3–4 are more sensitive than adults to KSI- 4088 in assay of migration. Expand
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