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Epidermal Growth Factor Receptor Activation of Calpain Is Required for Fibroblast Motility and Occurs via an ERK/MAP Kinase Signaling Pathway*
To become migratory, cells must reorganize their connections to the substratum, and during locomotion they must break rear attachments. The molecular and biochemical mechanisms underlying theseExpand
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Antitumor agents, 75. Synthesis of cytotoxic anthraquinones digiferruginol and morindaparvin-B.
  • P. Chang, K. Lee
  • Chemistry, Medicine
  • Journal of natural products
  • 1 November 1985
A simple and efficient synthesis of digiferruginol (4) and morindaparvin-B (10) is described. Marschalk reaction of 1-hydroxyanthraquinone afforded 1-hydroxy-2-methylanthraquinone (2). Treatment of 2Expand
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Reciprocal day/night relationship between serotonin oxidation and N-acetylation products in the rat pineal gland.
Pineal tryptophan, serotonin [5-hydroxytryptamine (5-HT)], N-acetylserotonin, melatonin, 5-hydroxyindoleacetic acid, 5-hydroxytryptophol, 5-methoxytryptophol, and 5-methoxyindoleacetic acid wereExpand
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Partial digestion of neurophysins with proteolytic enzymes: unusual interactions between bovine neurophysin II and chymotrypsin.
Bovine neurophysin II was partially digested by chymotrypsin and by chymotrypsin followed by carboxy-peptidase B to produce large fragments collectively representing deletions of residues 1-5 andExpand
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Hydrophobic interactions in human casein micelle formation: beta-casein aggregation.
The association of non-phosphorylated (0-P) and fully phosphorylated (5-P) human beta-caseins was studied by fluorescence spectroscopy and laser light scattering. The tryptophan fluorescenceExpand
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Interactions of triply phosphorylated human beta-casein: monomer characterization and hydrodynamic studies of self-association.
The triply phosphorylated form of human beta-casein comprises about 15% of that fraction and is thus a significant component about midway between the two extremes of zero and five phosphoryls. ItsExpand
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Interactions of triply phosphorylated human beta-casein: fluorescence spectroscopy and light-scattering studies of conformation and self-association.
Structural changes of triply phosphorylated human beta-casein, caused by shifts in temperature between 5 and 40 degrees C, were studied using intrinsic and extrinsic fluorescence, fluorescenceExpand
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Interaction properties of doubly phosphorylated beta-casein, a major component of the human milk caseins.
Doubly phosphorylated beta-casein constitutes nearly 30% of the total human beta-caseins and is thus one of the major components of that fraction. The properties and mode of association of doublyExpand
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Progress in the treatment of osteosarcoma.
  • P. Chang
  • Medicine
  • The Medical clinics of North America
  • 1 September 1977
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