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Integration of quanta in cerebellar granule cells during sensory processing
To understand the computations performed by the input layers of cortical structures, it is essential to determine the relationship between sensory-evoked synaptic input and the resulting pattern ofExpand
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High-fidelity transmission of sensory information by single cerebellar mossy fibre boutons
Understanding the transmission of sensory information at individual synaptic connections requires knowledge of the properties of presynaptic terminals and their patterns of firing evoked by sensoryExpand
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Bistability of cerebellar Purkinje cells modulated by sensory stimulation
A persistent change in neuronal activity after brief stimuli is a common feature of many neuronal microcircuits. This persistent activity can be sustained by ongoing reverberant network activity orExpand
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Methods for predicting cortical UP and DOWN states from the phase of deep layer local field potentials
We find that UP/DOWN states in deep cortical layers of rat primary auditory cortex (A1) are predictable from the phase of LFP at low frequencies (< 4 Hz). Expand
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Tonic Inhibition Enhances Fidelity of Sensory Information Transmission in the Cerebellar Cortex
Tonic inhibition is a key regulator of neuronal excitability and network function in the brain, but its role in sensory information processing remains poorly understood. The cerebellum is a favorableExpand
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How do neurons work together? Lessons from auditory cortex
Recordings of single neurons have yielded great insights into the way acoustic stimuli are represented in auditory cortex. However, any one neuron functions as part of a population whose combinedExpand
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The cerebellum linearly encodes whisker position during voluntary movement
Active whisking is an important model sensorimotor behavior, but the function of the cerebellum in the rodent whisker system is unknown. We have made patch clamp recordings from Purkinje cells inExpand
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Serial processing of kinematic signals by cerebellar circuitry during voluntary whisking
Purkinje cells (PCs) in Crus 1 represent whisker movement via linear changes in firing rate, but the circuit mechanisms underlying this coding scheme are unknown. Here we examine the role of upstreamExpand
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The Synaptic Representation of Sound Source Location in Auditory Cortex
A key function of the auditory system is to provide reliable information about the location of sound sources. Here, we describe how sound location is represented by synaptic input arriving ontoExpand
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Sensory-evoked synaptic integration in cerebellar and cerebral cortical neurons
Neurons integrate synaptic inputs across time and space, a process that determines the transformation of input signals into action potential output. This article explores how synaptic integrationExpand
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