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Initial Acquisition of Mutans Streptococci by Infants: Evidence for a Discrete Window of Infectivity
TLDR
It is reported for the first time that MS is acquired by infants during a defined period in the ontogeny of a child during a discrete period the authors designated as the "window of infectivity".
Expanding the biotechnology potential of lactobacilli through comparative genomics of 213 strains and associated genera
TLDR
The genome sequences of 213 Lactobacilli strains and associated genera are reported, and their encoded genetic catalogue for modifying carbohydrates and proteins are described, and a robust phylogenomic framework of existing species and for classifying new species is presented.
The Group I Strain of Streptococcus mutans, UA140, Produces Both the Lantibiotic Mutacin I and a Nonlantibiotic Bacteriocin, Mutacin IV
TLDR
Production of mutacins I and IV by UA140 appears to be regulated by different mechanisms under different physiological conditions, and the significance of producing two mutacin by one strain under different conditions and the implication of this property in terms of the ecology of S. mutans in the oral cavity are discussed.
Purification of Mutacin III from Group IIIStreptococcus mutans UA787 and Genetic Analyses of Mutacin III Biosynthesis Genes
TLDR
The cloned and sequenced the mutacin III biosynthesis gene locus from a group III strain of S. mutans, UA787, consistent with the supposition that mutac in III has posttranslational modifications similar to those of the lantibiotic epidermin.
Functional Analyses of the Promoters in the Lantibiotic Mutacin II Biosynthetic Locus in Streptococcus mutans
TLDR
Results suggest that expression of the mutacin operon is regulated by a complex system involving transcriptional and posttranscriptional or posttranslational controls.
Evidence-based clinical recommendations for the use of pit-and-fissure sealants: a report of the American Dental Association Council on Scientific Affairs.
TLDR
The expert panel concluded that sealants are effective in caries prevention and that sealant can prevent the progression of early noncavitated carious lesions.
The Fidelity of Initial Acquisition of Mutans Streptococci by Infants from Their Mothers
TLDR
The commonality of MS genotypes between mothers and their infants at the time of initial acquisition strongly suggests that MS strains were transmitted from mother to infant and that this transfer exhibited gender specificity.
Genotypic Diversity of Mutans Streptococci in Brazilian Nursery Children Suggests Horizontal Transmission
TLDR
Streptococcus mutans strains were isolated from cohorts of Brazilian nursery school children and genotyped by arbitrarily primed PCR and restriction fragment length polymorphism analysis, suggesting horizontal transmission.
Purification and Biochemical Characterization of Mutacin I from the Group I Strain of Streptococcus mutans, CH43, and Genetic Analysis of Mutacin I Biosynthesis Genes
TLDR
Comparison of the primary sequence of mutacin I with that of Mutacin III and epidermin suggests that mutacIn I likely has the same bridging pattern as epider Miners, possibly arising from a common ancestor.
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