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A fluorescence study of substrate and inhibitor binding to bovine liver dihydrofolate reductase.
- P. Degan, P. Carpano, G. Cercignani, G. Montagnoli
- Chemistry, Medicine
- The International journal of biochemistry
A competitive assay for MTX has been developed by exploiting the fluorescence enhancement of DHFR-bound FMTX, and may be useful for the routine determination of MTX in the concentration range from 10(-9) to 10(-7) M. Expand
Simultaneous Determination of Dispersion and Nonlinear Adsorption Parameters by Using Numerical Model and Optimization Techniques
The simultaneous determination of the dispersion and nonlinear adsorption (Freundlich or Languuir) parameters is obtained automatically by matching results of nuemerical models with experimental data… Expand