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Antibiotic prophylaxis and recurrent urinary tract infection in children.
Long-term, low-dose trimethoprim-sulfamethoxazole therapy was associated with a decreased number of urinary tract infections in predisposed children, and the treatment effect appeared to be consistent but modest across subgroups. Expand
Parents' attitudes to children's participation in randomized controlled trials.
OBJECTIVE To explore parents' attitudes to children's participation in randomized controlled trials. STUDY DESIGN Qualitative analysis of focus group discussions involving 33 parents from aExpand
Clinical trials in children
Issues relating to trial participation for children are explored and some strategies for improving the conduct of clinical trials involving children are suggested. Expand
Strategies for Increasing Recruitment to Randomised Controlled Trials: Systematic Review
Patrina Caldwell and colleagues performed a systematic review of randomized studies that compared methods of recruiting individual study participants into trials, and found that strategies that focusExpand
A systematic review on communicating with patients about evidence.
There is an increasing body of evidence supporting the design of effective evidence-based communication tools but variable access to such tools in practice, and values clarification exercises may be better than standard utility techniques for eliciting preferences in individual decision making. Expand
Impact of social media on the health of children and young people
The studies identified that the health impact of social media on children and young people was greatest on mental health and specifically in the areas of self‐esteem and well‐being, with related issues around cyberbullying and ‘Facebook Depression’. Expand
Management of nocturnal enuresis
Current knowledge about the treatment of nocturnal enuresis, which is intermittent involuntary voiding during sleep in the absence of physical disease in a child aged 5 years or more, is reviewed. Expand
Clinical trials in children.
Although current regulations and initiatives are improving the scope, quantity and quality of trials in children, there are still deficiencies that need to be addressed to accelerate radically equitable access to evidence-based therapies in children. Expand
Pediatricians' attitudes toward randomized controlled trials involving children.
It is suggested that children's participation in trials will be enhanced by increasing pediatricians' awareness of RCTs through education and involvement in trials and by improving the gains-risk balance. Expand
“Teaching by humiliation” and mistreatment of medical students in clinical rotations: a pilot study
An understanding of “teaching by humiliation” as experienced by medical students in Australia is generated to generate a contemporary understanding of teaching by humiliation. Expand