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An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus
Hepatitis C virus (HCV) infection is a serious cause of chronic liver disease worldwide with more than 170 million infected individuals at risk of developing significant morbidity and mortality.Expand
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Imidazolinones: potent inhibitors of acetohydroxyacid synthase.
The imidazolinones, a new chemical class of herbicides, were shown to be uncompetitive inhibitors of acetohydroxyacid synthase from corn. This is the first common enzyme in the biosynthetic pathwayExpand
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Guar Seed ß-Mannan Synthase Is a Member of the Cellulose Synthase Super Gene Family
Genes for the enzymes that make plant cell wall hemicellulosic polysaccharides remain to be identified. We report here the isolation of a complementary DNA (cDNA) clone encodingone such enzyme,Expand
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Loxoscelism and necrotic arachnidism.
The Brown recluse spider has emerged into a potent venomous creature. Loxoscelism and necrotic arachnidism is not an infrequent medical problem. Spiders other than L. reclusa are capable ofExpand
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Consensus sequences for early iodination and hormonogenesis in human thyroglobulin.
Thyroglobulin from a human goiter, containing four atoms of iodine/molecule (660,000 daltons), was iodinated with Na 125I and KI in vitro to achieve a net addition of either 2 or 7.8 atoms ofExpand
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Current concepts in the classification of connective tissue diseases. Overlap syndromes and mixed connective tissue disease (MCTD).
New principles are discussed for the classification of the diffuse collagen diseases, particularly the mixed connective tissue disease (MCTD), with clinical and historical explanation. Emphasis inExpand
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An NS 3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus
F. D. Rodriguez, G. Resch and M. Ilijin-Jug for technical assistance and plant cultivation; E. Jokitalo for TEM; M. Laxell and S. Tähtiharju for material; I. Bancroft and K. van de Sande atExpand
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A Proteomics Approach to Cloning Fenestrin from the Nuclear Exchange Junction of Tetrahymena
ABSTRACT. We set out to find the “fenestrin” gene, a gene whose protein is associated with numerous cellular apertures, including the nuclear exchange junction in mating Tetrahymena thermophila.Expand
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Herbicide-tolerant mutants of corn
Eight imidazolinone herbicide resistant corn cell lines were obtained from in vitro cell culture selections. Plants were regenerated from five of the lines and resistant progeny obtained from four.Expand
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Peritoneal dialysis for psoriasis. An uncontrolled study.
Remissions of long-standing psoriasis have been reported in patients starting either chronic hemodialysis or peritoneal dialysis for renal failure. To see if dialysis influences the course ofExpand
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