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Hydrogels in pharmaceutical formulations.
- N. Peppas, P. Bureš, W. Leobandung, H. Ichikawa
- Chemistry, Medicine
- European journal of pharmaceutics and…
- 3 July 2000
The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices. Expand
Genome size and DNA base composition of geophytes: the mirror of phenology and ecology?
Although geophytism together with producing larger cells appears to be an advantageous strategy for fast development of an organism in seasonal habitats, the drought sensitivity of large stomata may restrict the occurrence of geophytes with very large genomes to regions not subject to water stress. Expand
Ecological and evolutionary significance of genomic GC content diversity in monocots
- P. Šmarda, P. Bureš, +6 authors O. Rotreklová
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 15 September 2014
Significance Our large-scale survey of genomic nucleotide composition across monocots has enabled the first rigorous testing, to our knowledge, of its biological significance in plants. We show that… Expand
Genome size and GC content evolution of Festuca: ancestral expansion and subsequent reduction.
The present study indicates the high potential of general quantitative characters of the genome for understanding the long-term processes of genome evolution, testing evolutionary hypotheses and their usefulness for large-scale genomic projects. Expand
Ancestral Chromosomal Blocks Are Triplicated in Brassiceae Species with Varying Chromosome Number and Genome Size1
These findings provide compelling evidence of an ancient hexaploidization event and corresponding whole-genome triplication shared by the tribe Brassiceae, demonstrating the usefulness of comparative cytogenetics for elucidation of phylogenetic relationships. Expand
Understanding intraspecific variation in genome size in plants
The recent progress in understanding the spatio-temporal dynamics of intraspecific variation in genome size caused by the gradual accumulation of mutations is reviewed. Expand
Evolution of genome size in Carex (Cyperaceae) in relation to chromosome number and genomic base composition.
It is concluded that the evolution of genome and karyotype in Carex is promoted by frequent chromosomal fissions/fusions, rare polyploidy and common repetitive DNA proliferation/removal. Expand
Diverse retrotransposon families and an AT-rich satellite DNA revealed in giant genomes of Fritillaria lilies.
- Kateřina Ambrožová, T. Mandáková, +5 authors M. Lysak
- Biology, Medicine
- Annals of botany
- 1 February 2011
It is hypothesized that the genome obesity in Fritillaria may be partly determined by the failure of removal mechanisms to counterbalance effectively the retrotransposon amplification, and the giant Fritills seem to be composed of many diversified families of transposable elements. Expand
Genome size variation in Central European species of Cirsium (Compositae) and their natural hybrids.
Considerable differences in nuclear DNA content exist among Central European species of Cirsium on the diploid level and a negative relationship was detected between the genome size and the tendency to form natural interspecific hybrids. Expand
Genome size and genomic GC content evolution in the miniature genome-sized family Lentibulariaceae.
- A. Veleba, P. Bureš, L. Adamec, P. Šmarda, Ivana Lipnerová, L. Horová
- Biology, Medicine
- The New phytologist
- 1 July 2014
The absence of correlation between genomic parameters and ecological variables suggests that the driving forces of miniaturization are of intrinsic nature, and the extreme dynamics of Lentibulariaceae genomes provides a unique opportunity for studying genomeminiaturization and GC content variation. Expand