Brugada syndrome: report of the second consensus conference: endorsed by the Heart Rhythm Society and the European Heart Rhythm Association.
The present report elaborates further on the diagnostic criteria and examines risk stratification schemes and device and pharmacological approaches to therapy on the basis of the available clinical and basic science data.
Right bundle branch block, persistent ST segment elevation and sudden cardiac death: a distinct clinical and electrocardiographic syndrome. A multicenter report.
Task Force on Sudden Cardiac Death of the European Society of Cardiology.
The members of the Task Force on Sudden Death dedicate this paper to the memory of their former friend and colleague, Professor Ronald W. F. Campbell, who spent his life working in the field of sudden cardiac death, and the extent of the expanding knowledge in this field is described.
Genetic basis and molecular mechanism for idiopathic ventricular fibrillation
It is shown that sodium channels with the missense mutation recover from inactivation more rapidly than normal and that the frameshift mutation causes the sodium channel to be non-functional.
Brugada syndrome: report of the second consensus conference.
Sudden Death Associated With Short-QT Syndrome Linked to Mutations in HERG
The genetic basis for a new clinical entity characterized by sudden death and short-QT intervals in the ECG is described and a novel genetic and biophysical mechanism responsible for sudden death in infants, children, and young adults caused by mutations in KCNH2 is demonstrated.
Proposed diagnostic criteria for the Brugada syndrome: consensus report.
The electrocardiographic signature of the Brugada syndrome is dynamic and often concealed, but can be unmasked by potent sodium channel blockers such as flecainide, ajmaline, and procainamide, although the specificity of this effect for uncovering patients at risk for sudden death has been an issue of concern.
A New Approach to the Differential Diagnosis of a Regular Tachycardia With a Wide QRS Complex
New, simpler criteria are identified and incorporated in a stepwise approach that provides better sensitivity and specificity for making a correct diagnosis of ventricular tachycardia and may prevent diagnostic mistakes.
An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing.
Long-Term Follow-Up of Individuals With the Electrocardiographic Pattern of Right Bundle-Branch Block and ST-Segment Elevation in Precordial Leads V1 to V3
An ECG showing right bundle-branch block and ST-segment elevation in the right precordial leads is a marker of malignant ventricular arrhythmias and sudden death.