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Macromolecular size-and-shape distributions by sedimentation velocity analytical ultracentrifugation.
Sedimentation velocity analytical ultracentrifugation is an important tool in the characterization of macromolecules and nanoparticles in solution. The sedimentation coefficient distribution c(s) of… Expand
Studying multisite binary and ternary protein interactions by global analysis of isothermal titration calorimetry data in SEDPHAT: Application to adaptor protein complexes in cell signaling
- J. Houtman, P. Brown, +4 authors P. Schuck
- Chemistry, Medicine
- Protein science : a publication of the Protein…
- 1 January 2007
Multisite interactions and the formation of ternary or higher‐order protein complexes are ubiquitous features of protein interactions. Cooperativity between different ligands is a hallmark for… Expand
On the distribution of protein refractive index increments.
The protein refractive index increment, dn/dc, is an important parameter underlying the concentration determination and the biophysical characterization of proteins and protein complexes in many… Expand
Climate Change Affects Winter Chill for Temperate Fruit and Nut Trees
Background Temperate fruit and nut trees require adequate winter chill to produce economically viable yields. Global warming has the potential to reduce available winter chill and greatly impact crop… Expand
Permeability of Boric Acid Across Lipid Bilayers and Factors Affecting It
Boron enters plant roots as undissociated boric acid (H3BO3). Significant differences in B uptake are frequently observed even when plants are grown under identical conditions. It has been theorized… Expand
Co-repressor induced order and biotin repressor dimerization: a case for divergent followed by convergent evolution.
- Z. Wood, L. Weaver, P. Brown, D. Beckett, B. Matthews
- Biology, Medicine
- Journal of molecular biology
- 24 March 2006
BirA catalyzes the adenylation and subsequent covalent attachment of biotin to the biotin carboxyl carrier protein (BCCP). In the absence of apo-BCCP, biotin-5'-AMP acts as a co-repressor that… Expand
Kinetic analysis of boron transport in Chara
Abstract. The permeability of biological membranes to boric acid was investigated using the giant internodal cells of the charophyte alga Chara corallina (Klein ex Will. Esk. R.D. Wood). The… Expand
Dual strategies for peptidoglycan discrimination by peptidoglycan recognition proteins (PGRPs).
- Chittoor P Swaminathan, P. Brown, +6 authors R. Mariuzza
- Biology, Medicine
- Proceedings of the National Academy of Sciences…
- 17 January 2006
The innate immune system constitutes the first line of defense against microorganisms in both vertebrates and invertebrates. Although much progress has been made toward identifying key receptors and… Expand
A new adaptive grid-size algorithm for the simulation of sedimentation velocity profiles in analytical ultracentrifugation
A new adaptive grid-size ultracentrifugation algorithm for sedimentation velocity analysis, in particular, for the study of multi-component macromolecular mixtures. Expand
Characterizing Protein‐Protein Interactions by Sedimentation Velocity Analytical Ultracentrifugation
This unit introduces the basic principles and practice of sedimentation velocity analytical ultracentrifugation for the study of reversible protein interactions, such as the characterization of… Expand