• Publications
  • Influence
Assessing risk of bias in prevalence studies: modification of an existing tool and evidence of interrater agreement.
OBJECTIVE In the course of performing systematic reviews on the prevalence of low back and neck pain, we required a tool to assess the risk of study bias. Our objectives were to (1) modify anExpand
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A comparison of outcomes in osteoarthritis patients undergoing total hip and knee replacement surgery.
OBJECTIVE The aims of this study were to assess changes in physical function and quality of life with the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and the instrument ofExpand
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Does colchicine work? The results of the first controlled study in acute gout.
We have performed the first controlled study of colchicine in acute gout, to determine its efficacy and toxicity, and to define the natural history of acute gout. Two-thirds of colchicine-treatedExpand
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Nonsteroidal antiinflammatory drugs--differences and similarities.
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Impact of osteoarthritis on individuals and society: how much disability? Social consequences and health economic implications.
  • P. Brooks
  • Medicine
  • Current opinion in rheumatology
  • 1 September 2002
Osteoarthritis is a major cause of disability in both the developed and developing world. With the population aging, the prevalence of osteoarthritis is increasing and its consequences are impactingExpand
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OMERACT: An international initiative to improve outcome measurement in rheumatology
OMERACT is the acronym for an international, informally organized network initiated in 1992 aimed at improving outcome measurement in rheumatology. Chaired by an executive committee, it organizesExpand
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Interpreting the clinical significance of the differential inhibition of cyclooxygenase-1 and cyclooxygenase-2.
The International Consensus Meeting on the Mode of Action of COX-2 Inhibition (ICMMAC) brought together 17 international experts in arthritis, gastroenterology and pharmacology on 5 6 December 1997.Expand
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Clinical Pharmacokinetics of the Salicylates
SummaryThe use of salicylates in rheumatic diseases has been established for over 100 years. The more recent recognition of their modification of platelet and endothelial cell function has lead toExpand
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Circulating cytokine levels in patients with rheumatoid arthritis: results of a double blind trial with sulphasalazine.
Interleukin 1 (IL-1), IL-6, and tumour necrosis factor (TNF) alpha are pleiotropic cytokines produced predominantly by macrophages which have been implicated in the pathogenesis of rheumatoidExpand
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Simulation in clinical teaching and learning
Simulation‐based education (SBE) is a rapidly developing method of supplementing and enhancing the clinical education of medical students. Clinical situations are simulated for teaching and learningExpand
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