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Chronic Thromboembolic Pulmonary Hypertension (CTEPH): Results From an International Prospective Registry
Despite similarities in clinical presentation, operable and nonoperable CTEPH patients may have distinct associated medical conditions.
Pulmonary arterial hypertension in congenital heart disease: an epidemiologic perspective from a Dutch registry.
Long-Term Outcome of Patients With Chronic Thromboembolic Pulmonary Hypertension: Results From an International Prospective Registry
The long-term prognosis of operated patients currently is excellent and better than the outcome of not-operated patients, and pulmonary arterial hypertension–targeted therapy did not affect survival estimates significantly.
Mechanical Ventilation with Lower Tidal Volumes and Positive End-expiratory Pressure Prevents Pulmonary Inflammation in Patients without Preexisting Lung Injury
The use of lower tidal volumes and PEEP may limit pulmonary inflammation in mechanically ventilated patients without preexisting lung injury and the specific contribution of both lower tidalvolume and PEP on the protective effects of the lung should be further investigated.
Ventilator-induced Lung Injury Is Mediated by the NLRP3 Inflammasome
Background: The innate immune response is important in ventilator-induced lung injury (VILI) but the exact pathways involved are not elucidated. The authors studied the role of the intracellular…
Mechanical Ventilation with Lower Tidal Volumes and Positive End-expiratory Pressure Prevents Alveolar Coagulation in Patients without Lung Injury
Mechanical ventilation with higher tidal volumes and no PEEP promotes procoagulant changes, which are largely prevented by the use of lower tidalvolume and PEEP.
Effectiveness of discontinuing antibiotic treatment after three days versus eight days in mild to moderate-severe community acquired pneumonia: randomised, double blind study
Discontinuing amoxicillin treatment after three days is not inferior to discontinuing it after eight days in adults admitted to hospital with mild to moderate-severe community acquired pneumonia who substantially improved after an initial three days' treatment.
Antiinflammatory effects of salmeterol after inhalation of lipopolysaccharide by healthy volunteers.
- N. Maris, A. D. de Vos, T. van der Poll
- Biology, MedicineAmerican Journal of Respiratory and Critical Care…
- 1 October 2005
Salmeterol exerts antiinflammatory effects in the pulmonary compartment of humans exposed to LPS, while not significantly influencing other responses.
Right ventricular failure following chronic pressure overload is associated with reduction in left ventricular mass: evidence for atrophic remodeling.
Toll-like receptor mRNA levels in alveolar macrophages after inhalation of endotoxin
In conclusion, lipopolysaccharide differentially influences the toll-like receptor mRNA expression profile in human alveolar macrophages in vivo.