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BRAF alteration status and the histone H3F3A gene K27M mutation segregate spinal cord astrocytoma histology
- G. Shankar, Nina Lelic, +17 authors M. Meyerson
- Medicine, Biology
- Acta Neuropathologica
- 20 October 2015
Intramedullary spinal cord neoplasms represent 2–4 % of central nervous system tumors, of which astrocytic gliomas represent 80 %. Patients presenting with spinal cord astrocytomas span the… Expand
Tuberculosis-associated haemophagocytic syndrome.
- P. Brastianos, J. Swanson, M. Torbenson, John Sperati, P. Karakousis
- The Lancet. Infectious diseases
- 1 July 2006
Haemophagocytic syndrome is a disorder characterised by fevers, lymphadenopathy, hepatosplenomegaly, cytopenias, and hyperferritinaemia due to dysregulated activation and proliferation of… Expand
Solitary Thoracic Osteochondroma: Case Report and Review of the Literature
OBJECTIVE AND IMPORTANCE: Osteochondromas are common benign bone tumors that rarely arise in the vertebral column. Intraspinal presentation of these tumors is usually circumscribed to the cervical… Expand
Aneurysmal bone cysts of the sacrum: a report of ten cases and review of the literature.
Ten cases of aneurysmal bone cysts are presented. Patients ranged in age from five years to 64 years. Treatment was resection or curettage; four patients had preoperative embolization. Treatment… Expand
TERT promoter mutations in progressive treatment-resistant meningiomas.
2047Background: Recurrent meningiomas often undergo a grade-progression to become atypical or malignant upon recurrence. Detailed study of progressive meningioma has been hampered by the lack of… Expand
BM-07GENOMIC CHARACTERIZATION OF BRAIN METASTASES REVEALS BRANCHED EVOLUTION AND METASTASIS-SPECIFIC MUTATIONS
BACKGROUND: Brain metastases are the most common intracranial tumors in adults. We have a limited understanding of how brain metastases evolve from their primary tumor. Our objectives were to (1)… Expand
Erratum: A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases (S0092867418301156 (2018) 172(5) (1050–1062.e14) (S0092867418301156) (10.1016/j.cell.2018.01.038))
Precision Medicine for Primary Central Nervous System Tumors: Are We There Yet?
- Franziska M Ippen, H. Colman, M. J. van den Bent, P. Brastianos
- American Society of Clinical Oncology educational…
- 23 May 2018
In recent years, technologic advances have increased tremendously our understanding of the molecular characteristics and genetic drivers of a variety of brain tumors. These discoveries have led to… Expand
Abstract 3178: Can DNA from archived formalin-fixed paraffin embedded (FFPE) cancer tissues be used for somatic mutation analysis in next generation sequencing
Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL Formalin-fixed paraffin embedded (FFPE) tissues are far more abundant in most tissue banks and pathology departments… Expand
TERT Alterations in Progressive Treatment-Resistant Meningiomas.