• Publications
  • Influence
International Agency for Research on Cancer.
TLDR
Applications for a training fellowship in 2014-2015 are invited from postdoctoral scientists who intend to pursue a career in cancer research and wish to complete their training in those aspects of cancer research related to the Agency’s mission. Expand
Metabolic gene polymorphism frequencies in control populations.
TLDR
Using the International Project on Genetic Susceptibility to Environmental Carcinogens (GSEC) database containing information on over 15,000 control (noncancer) subjects, the allele and genotype frequencies for many of the more commonly studied metabolic genes in the human population were determined. Expand
Molecular epidemiology.
TLDR
If biomarkers offer new opportunities to overcome some of the limitations of epidemiology, their added value over traditional approaches should be systematically assessed. Expand
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25
TLDR
The results provide compelling evidence of a locus at 15q25 predisposing to lung cancer, and reinforce interest in nicotinic acetylcholine receptors as potential disease candidates and chemopreventative targets. Expand
Genetic polymorphisms in the base excision repair pathway and cancer risk: a HuGE review.
TLDR
A meta-analyses of associations between genes in the base excision repair pathway and cancer risk, focusing on three key genes, found increased lung cancer risk among subjects carrying the OGG1 Cys/Cys genotype and a protective effect of the XRCC1 194Trp allele for tobacco-related cancers. Expand
Association between body-mass index and risk of death in more than 1 million Asians.
TLDR
Underweight was associated with a substantially increased risk of death in all Asian populations, however, the excess risk of died was seen among East Asians but not among Indians and Bangladeshis. Expand
Cancer risk from occupational and environmental exposure to polycyclic aromatic hydrocarbons
TLDR
The lung seems to be the major target organ of PAH carcinogenicity and increased risk is present in most of the industries and occupations listed above, and the results of studies addressing environmental PAH exposure are consistent with these conclusions. Expand
Smokeless tobacco and cancer.
TLDR
Use of smokeless tobacco products is common worldwide, with increasing consumption in many countries, and epidemiological data from the USA and Asia show a raised risk of oral cancer, but this is not confirmed in northern European studies. Expand
Assessment of cumulative evidence on genetic associations: interim guidelines.
TLDR
A proposed semi-quantitative index assigns three levels for the amount of evidence, extent of replication, and protection from bias, and also generates a composite assessment of 'strong', 'moderate' or 'weak' epidemiological credibility. Expand
Modified Mediterranean diet and survival: EPIC-elderly prospective cohort study
TLDR
The Mediterranean diet, modified so as to apply across Europe, was associated with increased survival among older people and no statistically significant evidence of heterogeneity was found. Expand
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